...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of clinical psychiatry >Prolactin-related and metabolic adverse effects of atypical antipsychotic agents.
【24h】

Prolactin-related and metabolic adverse effects of atypical antipsychotic agents.

机译：非典型抗精神病药的催乳素相关和代谢不良反应。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

While there are many effective antipsychotics available to clinicians for treating schizophrenia or bipolar mania, the onset of antipsychotic-associated prolactin-related and metabolic adverse effects can diminish the effectiveness of treatment. Increased levels of prolactin (hyperprolactinemia) associated with some antipsychotics raises the risk of sexual side effects. The increased appetite and/or sedation (reduced activity levels) induced by other antipsychotics can lead to weight gain, dyslipidemia, and high blood pressure and, if unchecked, ultimately to cardiovascular disease, diabetes, and metabolic syndrome. Clinicians should take steps to help their patients avoid unnecessary risks associated with antipsychotic use. These steps include monitoring risk factors for developing these illnesses by taking careful patient histories and baseline measurements of patients' weight and blood chemistry. Patients should be made aware of potential metabolic and prolactin-related side effects, and periodic checks should also be made to watch for changes in weight, body mass index, waist size, blood pressure, fasting glucose, or lipid levels that could be harmful and may increase risk for cardiovascular disease.
机译：尽管临床医生可以使用许多有效的抗精神病药来治疗精神分裂症或躁郁症，但是与抗精神病药相关的催乳激素相关和代谢不良反应的发作会降低治疗的有效性。与某些抗精神病药有关的催乳素（高催乳素血症）水平升高会增加发生性副作用的风险。其他抗精神病药引起的食欲和/或镇静作用增加（活动水平降低）会导致体重增加，血脂异常和高血压，如果不加检查，最终会导致心血管疾病，糖尿病和代谢综合征。临床医生应采取措施帮助患者避免使用抗精神病药带来的不必要风险。这些步骤包括通过仔细观察患者的病史以及对患者体重和血液化学成分进行基线测量来监测患这些疾病的危险因素。应该使患者意识到可能的代谢和催乳激素相关的副作用，还应定期检查以观察体重，体重指数，腰围大小，血压，空腹血糖或血脂水平的变化，这些变化可能有害和有害。可能会增加患心血管疾病的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号