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首页> 外文期刊>The journal of clinical psychiatry >Effectiveness of brief cognitive-behavioral therapy for schizophrenia delivered by mental health nurses: relapse and recovery at 24 months.
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Effectiveness of brief cognitive-behavioral therapy for schizophrenia delivered by mental health nurses: relapse and recovery at 24 months.

机译：心理保健护士对精神分裂症进行简短认知行为疗法的有效性：24个月复发和恢复。

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BACKGROUND: Evidence of the efficacy of cognitive-behavioral therapy (CBT) for schizophrenia is increasing. There are very few studies of effectiveness, especially in the medium term. OBJECTIVE: To evaluate the durability of the effect of brief CBT provided by mental health nurses in community-based patients with schizophrenia (diagnosed according to ICD-10 research criteria), using time to relapse as primary outcome and days hospitalized and occupational recovery as secondary outcomes at 24-month follow-up. METHOD: A 2:1 randomized trial, conducted from 1999 to 2003, was performed to evaluate the effects of brief CBT delivered by mental health nurses trained over 10 days with ongoing supervision compared to treatment as usual (TAU), with measurement performed by raters blind to treatment allocation. RESULTS: 205 (79.8%) of 257 CBT patients and 125 (75.8%) of 165 TAU patients could be followed up at 24 months. Of 205 patients in the CBT group, 64 (31.2%) relapsed, versus 57 (45.6%) of 125 patients in the TAU group (p = .02). Patients rehospitalized from the CBT group spent a total of 6710 days in hospital (mean = 32.7 days), while those from the TAU group were inpatients for 6114 days (mean = 48.9 days) (p < .05). Twenty-one (10.2%) of 205 patients made an occupational recovery in the CBT group, and 17 (13.6%) of 125, in the TAU group (chi(2) test not significant). Mean time to relapse was 356.8 days (SD = 241.9 days) for the CBT group and 296.1 days (SD = 215.7 days) for the TAU group (OR = 1.592, 95% CI = 1.038 to 2.441, p = .033). CONCLUSION: Beneficial effects on relapse and rehospitalization following brief CBT delivered by mental health nurses in community-based patients with schizophrenia are maintained at 24-month follow-up. Occupational recovery is not improved by brief CBT.
机译：背景：认知行为疗法（CBT）治疗精神分裂症的有效性的证据正在增加。关于有效性的研究很少，特别是在中期。目的：评估精神卫生护士对社区精神分裂症患者（根据ICD-10研究标准诊断）进行短暂CBT效果的持久性，以复发时间为主要结果，住院和职业恢复时间为次要24个月的随访结果。方法：从1999年至2003年进行了一项2：1随机试验，以评估在持续监督下经过10天培训的精神卫生护士与常规治疗（TAU）相比，短暂CBT的效果，并由评估者进行评估对治疗分配无知。结果：257名CBT患者中的205名（79.8％）和165名TAU患者中的125名（75.8％）可在24个月时得到随访。 CBT组的205例患者中有64例（31.2％）复发，而TAU组的125例中有57例（45.6％）复发（p = .02）。从CBT组住院的患者总共住院了6710天（平均= 32.7天），而从TAU组住院的患者住院了6114天（平均= 48.9天）（p <.05）。 205例患者中有21例（10.2％）在CBT组中恢复了职业恢复，而TAU组中的17例（13.6％）在125例中恢复了职业（chi（2）测试不显着）。 CBT组的平均复发时间为356.8天（SD = 241.9天），TAU组的平均复发时间为296.1天（SD = 215.7天）（OR = 1.592，95％CI = 1.038至2.441，p = .033）。结论：精神卫生护士对社区精神分裂症患者进行短暂的CBT治疗后，对复发和再次住院的有益影响维持在24个月的随访中。简短的CBT不能改善职业恢复。

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