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首页> 外文期刊>The journal of clinical psychiatry >Family outcomes from a randomized control trial of relapse prevention therapy in first-episode psychosis.
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Family outcomes from a randomized control trial of relapse prevention therapy in first-episode psychosis.

机译：家庭复发来自于首发精神病复发预防治疗的随机对照试验。

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OBJECTIVE: We have previously reported that our combined individual and family cognitive-behavioral therapy (CBT) relapse prevention therapy (RPT) was effective in reducing relapse rates compared to treatment as usual (TAU) within a specialist program for young, first-episode psychosis patients who had reached remission on positive symptoms. Here, we report the outcomes for family participants of DSM-IV-diagnosed first-episode psychosis patients recruited between November 2003 and May 2005 over a 2.5-year follow-up period. The primary hypothesis was that, compared to family members receiving TAU, family participants who received RPT would have significantly improved appraisals of stressors related to caregiving. Secondary hypotheses were that RPT would be associated with reduced expressed emotion and improved psychological distress. METHOD: Family members were assessed at baseline and at 7-month, 12-month, 18-month, 24-month, and 30-month follow-up on appraisal of caregiving, expressed emotion, and psychological distress using the Experience of Caregiving Inventory, The Family Questionnaire, and the General Health Questionnaire of 28 Items, respectively. The family component of RPT was based on family behavioral therapy for schizophrenia with a specific focus on psychoeducation and CBT for relapse prevention. RESULTS: Thirty-two families received RPT, and 31 families received TAU. There were significant group effects for aspects of the appraisal of caregiving, including negative symptoms, positive personal experiences, and total positive score on the Experience of Caregiving Inventory. Time effects were evident for emotional overinvolvement and for aspects of the appraisal of caregiving. There were no significant effects for psychological distress. CONCLUSIONS: The relatives of patients who received RPT perceived less stress related to their relative's negative symptoms and an increase in perceived opportunities to make a positive contribution to the care of their relative compared to carers in the TAU condition. Cognitive-behavioral therapy for relapse prevention showed promise in improving the experience of caregiving for family members of first-episode psychosis patients over a 2.5-year follow-up period. TRIAL REGISTRATION: anzctr.org.au Identifier: ACTRN12605000514606.
机译：目的：我们以前曾报道，在针对年轻的首发性精神病的专项计划中，与常规治疗（TAU）相比，我们的个人和家庭认知行为疗法（CBT）复发预防疗法（RPT）联合有效降低了复发率症状已经缓解的患者。在这里，我们报告了在2.5年的随访期内2003年11月至2005年5月之间招募的DSM-IV诊断的首发精神病患者的家庭参与者的结局。主要假设是，与接受TAU的家庭成员相比，接受RPT的家庭参与者将大大改善与护理有关的压力源评估。次要假设是RPT将与减少的表达情绪和改善的心理困扰有关。方法：使用照护经验清单对基线，在照护，表达情绪和心理困扰进行评估的基线以及7个月，12个月，18个月，24个月和30个月的家庭成员进行评估，家庭问卷和普通健康问卷共28项。 RPT的家庭组成部分基于针对精神分裂症的家庭行为疗法，尤其侧重于心理教育和CBT预防复发。结果：32个家庭接受了RPT，31个家庭接受了TAU。护理评估的各个方面均具有显着的群体效应，包括负面症状，积极的个人经历以及“护理清单经验”的总积极得分。情绪过度投入和护理评估方面的时间效应是显而易见的。对心理困扰没有显着影响。结论：与TAU患者相比，接受RPT的患者的亲属感觉更少的压力与亲戚的负面症状有关，并且增加了为亲戚的护理做出积极贡献的机会。预防复发的认知行为疗法在2.5年的随访期内有望改善首发精神病患者家属的照料体验。试用注册：anzctr.org.au标识符：ACTRN12605000514606。

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