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首页> 外文期刊>The journal of clinical psychiatry >Insomnia and Sleep Duration in a Large Cohort of Patients With Major Depressive Disorder and Anxiety Disorders
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Insomnia and Sleep Duration in a Large Cohort of Patients With Major Depressive Disorder and Anxiety Disorders

机译：大量患有严重抑郁症和焦虑症的患者的失眠和睡眠时间

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Objective: Disturbed sleep has a high impact on daily functioning and has been correlated with psychopathology. We investigated the extent to which insomnia and sleep duration were associated with both current and remitted depressive and anxiety disorders in a large-scale epidemio-logic study, taking sociodemographics, health factors, and medication use into account.Method: Data of 2,619 individuals from the Netherlands Study of Depression and Anxiety (NESDA) were analyzed. Psychopathology was classified as no, current, or remitted DSM-IV-based diagnosis of major depressive or anxiety disorder. Outcome measures were insomnia (Women's Health Initiative Insomnia Rating Scale score > 9) and sleep duration (< 6 hours, 7-9 hours, > 10 hours). Baseline measurement was conducted between September 2004 and February 2007.Results: Both current and remitted depressive disorder and current anxiety disorder were associated with insomnia and short sleep duration with odds ratios (ORs) for insomnia ranging from 1.42 to 3.23 and for short sleep duration ranging from 1.41 to 2.53. Associations were stronger for current than for remitted diagnoses and stronger for depressive than for anxiety disorders. Also long sleep duration was associated with current depressive disorder and anxiety disorders (OR range, 1.53-2.66). Sociodemographic factors, health indicators, and psychotropic medication use did contribute to sleep outcomes but could not explain much of the psychopathology and sleep associations.Conclusion: Depressive disorder-but also anxiety disorder-is strongly associated with sleep disturbances. Insomnia and short sleep duration persist after remittance of these disorders, suggesting that these are residual symptoms or possibly trait markers. Also, long sleep duration is associated with current depressive or anxiety disorders.
机译：目的：睡眠障碍对日常功能有很大影响，并与精神病理学有关。我们在一项大规模的流行病学研究中，研究了失眠和睡眠时间与当前和缓解的抑郁症和焦虑症相关的程度，方法包括社会人口统计学，健康因素和药物使用方法。方法：来自2619人的数据对荷兰抑郁症和焦虑症研究（NESDA）进行了分析。精神病理学分为基于重度抑郁或焦虑症的无，当前或已缓解的基于DSM-IV的诊断。结果指标为失眠（妇女健康倡议失眠评分量表评分> 9）和睡眠时间（<6小时，7-9小时，> 10小时）。在2004年9月至2007年2月之间进行了基线测量。结果：当前和缓解的抑郁症以及当前的焦虑症均与失眠和睡眠时间短有关，失眠的比值比（OR）为1.42至3.23，睡眠时间短从1.41到2.53。当前的关联性强于可疑诊断，而抑郁症的关联性强于焦虑症。长时间的睡眠也与当前的抑郁症和焦虑症有关（OR范围为1.53-2.66）。社会人口统计学因素，健康指标和精神药物的使用确实有助于睡眠结果，但不能解释很多精神病理学和睡眠关联。结论：抑郁症-以及焦虑症-与睡眠障碍密切相关。缓解这些疾病后，失眠和短暂的睡眠时间仍然存在，这表明这些是残留症状或可能是特征标记。另外，长时间的睡眠与当前的抑郁或焦虑症有关。

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