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首页> 外文期刊>The journal of clinical psychiatry >Predominance of Symptoms Over Time in Early-Onset Psychosis: A Principal Component Factor Analysis of the Positive and Negative Syndrome Scale
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Predominance of Symptoms Over Time in Early-Onset Psychosis: A Principal Component Factor Analysis of the Positive and Negative Syndrome Scale

机译：早期发作的精神病随时间推移的症状占主导地位：阳性和阴性综合征量表的主成分分析

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摘要

Background: Early-onset psychosis is a symp-tomatically nonspecific and heterogeneous entity composed of several diagnoses. This study examined the dimensional structure of symptoms and the temporal stability of this structure during a 6-month follow-up.Method: A principal component factor analysis of the Positive and Negative Syndrome Scale was conducted at baseline, 4 weeks, and 6 months in a sample of 99 first-episode psychotic patients (mean age = 15.5 years).Results: The factor analysis produced a 5-dimension solution (Positive, Negative, Depression, Cognitive, Hostility) that explained 62.4% of the variance at baseline, 63.4% at 4 weeks, and 65.1% at 6 months. Negative dimension was the most consistent and stable over time and was predominant at baseline (23.9%) and at 4 weeks (25.7%). Depression was predominant at 6 months (31.1%).Conclusions: There is a stable 5-dimension structure of symptoms in early-onset psychosis with varying predominance of symptoms over time. Negative symptoms are a core feature of psychosis and are thus important diagnostic criteria.
机译：背景：早发性精神病是一种有症状的非特异性异质实体，由多种诊断组成。本研究在6个月的随访期间检查了症状的维度结构和该结构的时间稳定性。方法：在基线，4周和6个月内对阳性和阴性综合征量表进行主成分因子分析。样本为99名首发精神病患者（平均年龄= 15.5岁）。结果：因子分析产生了5维解决方案（正面，负面，抑郁，认知，敌意），可以解释基线时62.4％的方差，即63.4。 4周时为％，6个月时为65.1％。负维度是随时间推移最一致且最稳定的维度，在基线（23.9％）和4周（25.7％）时占主导地位。抑郁症在6个月时占主导地位（31.1％）。结论：早发性精神病的症状具有稳定的5维结构，随着时间的推移，症状的变化也不同。阴性症状是精神病的核心特征，因此是重要的诊断标准。

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