首页> 外文期刊>The journal of clinical psychiatry >Increased Dipeptidyl Peptidase-4 Activity Is Associated With High Prevalence of Depression in Middle-Aged and Older Adults: A Cross-Sectional Study
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Increased Dipeptidyl Peptidase-4 Activity Is Associated With High Prevalence of Depression in Middle-Aged and Older Adults: A Cross-Sectional Study

机译:在中老年人中,二肽基肽酶-4活性增加与抑郁症的高患病率有关:一项跨领域研究

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摘要

Objective: Obesity, inflammation, and decreased neuropeptide Y (NPY) are risk factors for depression. Dipeptidyl peptidase-4 (DPP4), a newly identified adipokine, has been proved to promote inflammation and NPY degradation. Hence, we aimed to investigate the association between plasma DPP4 activity and depression symptoms in middle-aged and older adults.
机译:目的:肥胖,发炎和神经肽Y(NPY)降低是抑郁症的危险因素。二肽基肽酶-4(DPP4)是一种新近鉴定出的脂肪因子,已被证明能促进炎症和NPY降解。因此,我们旨在研究血浆DPP4活性与中老年人的抑郁症状之间的关系。

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