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首页> 外文期刊>The Journal of dermatology >Case of rheumatoid papules: Is this a fink between vasculitis and rheumatoid nodules?
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Case of rheumatoid papules: Is this a fink between vasculitis and rheumatoid nodules?

机译：类风湿丘疹病例：这是血管炎和类风湿结节之间的怪癖吗？

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A 63-year-old Japanese man had suffered from classic rheumatoid arthritis (RA) for 3 years with synovitis of the small joints of his hands and wrists. He had been diagnosed with RA based on the American Rheumatism Association criteria, and had been treated with sulfasalazine (1000 mg daily). He came to the Department of Dermatology at the University of Yaman-ashi in August 2011 with a 3-week history of a papular eruption on his hands. Cutaneous examination revealed skin-colored or slightly red, hard papules on the back and the side of his fingers (Fig. 1a,b). Laboratory examination revealed high levels of rheumatoid factor (84 lU/mL); however, antineutrophil cytoplas-mic autoantibody (ANCA) with a cytoplasmic fluorescence pattern (C-ANCA) and proteinase 3-specific (PR3)-ANCA were not detected. A skin biopsy was taken from the papule on the back of his finger. Histological examination showed a prominent mixed inflammatory cell infiltrate in the whole dermis, which comprised neutrophils, lymphocytes and histiocytes.
机译：一名63岁的日本男子患有典型的类风湿关节炎（RA）3年，手和腕部小关节滑膜炎。根据美国风湿病协会的标准，他被诊断出患有RA，并已接受柳氮磺吡啶（1000 mg /日）的治疗。他于2011年8月来到Yaman-ashi大学皮肤科，手上有3周的丘疹性喷发病史。皮肤检查发现手指的背面和侧面有皮肤色或略带红色的硬丘疹（图1a，b）。实验室检查发现类风湿因子水平很高（84 lU / mL）;但是，未检测到具有细胞质荧光图谱（C-ANCA）和蛋白酶3特异性（PR3）-ANCA的抗中性粒细胞胞质自身抗体（ANCA）。从他手指背面的丘疹上取了皮肤活检。组织学检查显示整个真皮中有明显的混合炎性细胞浸润，包括中性粒细胞，淋巴细胞和组织细胞。

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