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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Health outcomes of neonates with osteogenesis imperfecta: a cross-sectional study
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Health outcomes of neonates with osteogenesis imperfecta: a cross-sectional study

机译：新生儿成骨不全症的健康结局：一项横断面研究

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Objective: To assess at-birth health outcomes of neonates with osteogenesis imperfecta (OI).Study design: A total of 53 women who self-reported having had at least one child with OI completed the survey. We evaluated pregnancy length, neonatal intensive care unit (NICU) usage, at-birth complications, and the child's clinical information including OI type, height and weight.Results: Information was gathered on a total of 77 children (60 type I, 4 type III and 13 type IV). Health conditions reported at birth included breech presentation (24%), prematurity (27%), fracture (18%), bone deformity (18%) and respiratory problems (22%). Approximately 31% (n=24) received NICU care. There was a significant association between younger maternal age, preterm delivery and NICU admission.Conclusion: Our findings suggest that newborns with OI appear to be at high risk of skeletal disorders, preterm delivery and breech presentation. Younger maternal age and preterm delivery seem to be strong predictors of the need for NICU care. Our data suggest that pregnant women with OI younger than 20 years of age may benefit from added clinical supervision in anticipation of adverse effects on their child.
机译：目的：评估具有成骨不全症（OI）的新生儿在出生时的健康结局。研究设计：共有53名自我报告的妇女至少有一个OI的孩子完成了调查。我们评估了怀孕时间，新生儿重症监护病房（NICU）的使用情况，出生时的并发症以及包括OI类型，身高和体重在内的孩子的临床信息。结果：该信息收集了总共77名儿童（I型，4型）的信息。 III和13型IV）。出生时报告的健康状况包括臀位表现（24％），早产（27％），骨折（18％），骨畸形（18％）和呼吸系统疾病（22％）。大约31％（n = 24）得到了NICU护理。孕妇年龄，早产与NICU入院之间存在显着关联。结论：我们的研究结果表明，患有OI的新生儿似乎存在骨骼疾病，早产和臀位的高风险。较年轻的产妇年龄和早产似乎是需要重症监护病房的重要预测因素。我们的数据表明，OI年龄小于20岁的孕妇可以从增加的临床监督中受益，因为他们预期会对孩子产生不利影响。

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