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首页> 外文期刊>The Journal of maternal-fetal medicine >Sequential use of Prepidil and extra-amniotic saline infusion for the induction of labor in nulliparous women with very low Bishop scores.
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Sequential use of Prepidil and extra-amniotic saline infusion for the induction of labor in nulliparous women with very low Bishop scores.

机译：序贯使用Prepidil和羊水外输注在Bishop评分极低的未产妇中引产。

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OBJECTIVE: To evaluate the efficacy of sequential use of Prepidil (prostaglandin E2 gel) and extra-amniotic saline infusion for the induction of labor in nulliparous women with very low Bishop scores. STUDY DESIGN: Nulliparous women with singleton gestations, intact membranes and a cervical Bishop score of < or = 2 who received Prepidil gel and extra-amniotic saline infusion sequentially for the induction of labor between July 1996 and July 1998 were studied. RESULTS: Thirty-one women met the inclusion criteria. Indications for induction included post-dates (six of 31), pre-eclampsia (ten of 31), diabetes (three of 31), oligohydramnios (three of 31), intrauterine growth restriction (two of 31) and non-reactive non-stress test (NST) (seven of 31). The average time from onset of induction to delivery was 38.1 +/- 13.5 h. Vaginal delivery was achieved in 80.6%. Women requiring > 2 doses of Prepidil had a higher risk of delivering abdominally (OR = 3.5). Three of seven (42.9%) women with labor induced for non-reactive NST but only three of 24 (12.5%) with labor induced for other indications had a Cesarean section delivery (p < 0.001). CONCLUSIONS: Nulliparous women with very unfavorable cervices can be counselled that they have an 80% chance of vaginal delivery using sequential Prepidil and extra-amniotic saline infusion as an induction method, with 90% delivering within the first 48 h.
机译：目的：评估序贯使用Prepidil（前列腺素E2凝胶）和羊水外输注对Bishop评分极低的未产妇引产的功效。研究设计：研究了1996年7月至1998年7月间接受Prepidil凝胶和羊水额外输注以引产的具有单胎妊娠，胎膜完整和宫颈Bishop评分≤2的无脂肪妇女。结果：31名妇女符合纳入标准。诱导适应症包括约会后（31日中的六个），先兆子痫（31中的十个），糖尿病（31个中的三个），羊水过少（31个中的三个），宫内生长受限（31个中的两个）和非反应性非压力测试（NST）（31个中的7个）。从诱导开始到分娩的平均时间为38.1 +/- 13.5 h。阴道分娩率达到80.6％。需要> 2剂量Prepidil的妇女发生腹腔分娩的风险较高（OR = 3.5）。因非反应性NST而引产的七名女性中有三名（42.9％），但因其他适应症而引产的24名女性中只有三名（12.5％）剖宫产（p <0.001）。结论：对于宫颈不良妇女，可以建议他们使用Prepidil和羊水补充液作为诱导方法，有80％的机会进行阴道分娩，其中48％的机会在头48小时内分娩。

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