首页> 外文期刊>The Journal of Infectious Diseases >Household transmission of 2009 influenza A (H1N1) virus after a school-based outbreak in New York City, April-May 2009.
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Household transmission of 2009 influenza A (H1N1) virus after a school-based outbreak in New York City, April-May 2009.

机译:2009年4月至5月在纽约市发生学校爆发后,2009年甲型H1N1流感病毒的家庭传播。

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摘要

In April 2009, an outbreak due to infection with the 2009 pandemic influenza A (H1N1) virus (pH1N1) was investigated in a New York City high school. We surveyed household contacts of ill students to characterize the extent of transmission within households, identify contact groups at highest risk for illness, and assess the potential for preventing household transmission. Influenza-like illness (ILI) was reported by 79 of 702 household contacts (11.3% attack rate). Multivariate analysis showed that older age was protective: for each increasing year of age, the risk of ILI was reduced 5%. Additional protective factors included antiviral prophylaxis and having had a household discussion about influenza. Providing care for the index case patient and watching television with the index case patient were risk factors among parents and siblings, respectively. Fifty percent of cases occurred within 3 days of onset of illness in the student. These factors have implications for mitigating the impact of pH1N1 transmission.
机译:2009年4月,在纽约市一所中学对因2009年大流行性甲型流感(H1N1)病毒(pH1N1)感染而爆发的疫情进行了调查。我们调查了生病学生的家庭接触情况,以表征家庭内部传播的程度,确定患病风险最高的接触人群,并评估预防家庭传播的潜力。 702位家庭成员中有79位报告了流感样疾病(ILI)(发作率11.3%)。多变量分析表明,老年人具有保护性:每增加一个年龄,ILI的风险就会降低5%。其他保护因素包​​括抗病毒预防和关于流感的家庭讨论。照顾索引病人和与索引病人看电视分别是父母和兄弟姐妹中的危险因素。 50%的病例在学生发病后3天内发生。这些因素对减轻pH1N1传播的影响具有影响。

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