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首页> 外文期刊>The Journal of investigative dermatology. >Help in the diagnosis of melanoma?
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Help in the diagnosis of melanoma?

机译:帮助诊断黑色素瘤?

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摘要

The oft-quoted line "It is what I say it is" is commonly applied to dermato-logic diagnoses, and this saying can also be applied to histologic diagnoses. Whether evaluating a biopsy specimen at a single moment during the course of a disease accurately predicts the biologic course of that lesion is not always clear. This is especially true in the diagnosis of melanoma, in which excision of a potentially fatal lesion obviates learning its true biological potential. The alternative option-to leave untreated a lesion with unknown biologic potential-is unacceptable, because doing so places patients at risk (melanoma is predicted to kill nearly 9,000 Americans this year alone (American Cancer Society 2009)). Thus, the overarching goal for melanoma clinicians is to accurately diagnose and subsequently excise true melanomas while leaving the remainder untreated.
机译:经常被引用的行“这就是我所说的”通常用于皮肤病学诊断,这句话也可以用于组织学诊断。在疾病过程中的某个时刻评估活检标本是否可以准确预测该病变的生物学过程,并不总是很清楚。这在黑色素瘤的诊断中尤其如此,因为在黑色素瘤中切除可能致命的病灶可避免了解其真正的生物学潜力。另一种选择是不接受治疗,其生物学潜能未知,这是不可接受的,因为这样做会使患者处于危险之中(预计仅今年黑色素瘤就将杀死近9,000名美国人(美国癌症协会,2009年))。因此,黑色素瘤临床医生的首要目标是准确诊断并随后切除真正的黑色素瘤,同时不治疗其余的黑色素瘤。

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