Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes.

Tsutsumi M; Denda S; Ikeyama K; Goto M; Denda M

首页> 外文期刊>The Journal of investigative dermatology. >Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes.

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Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes.

机译：暴露于低温下会诱导培养的人角质形成细胞中细胞内钙的升高。

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The thermo-sensitive protein transient receptor potential cation channel sub- family A, member 1 (TRPA1) is activated by temperatures below 17degC and by several reagents, including allyl isothio- cyanate and cinnamaldehyde (Dhaka et al., 2006). Recently, expression of TRPA1 in human epidermis was reported (Atoyan et al, 2009). Thus, epidermal keratinocytes might have a sensory system that responds to low temperature. To test this idea, we examined the effects of low temperature and reagents that modulate TRPA1 on the intracellular calcium level of cultured human kerati-nocytes (for details, see Methods in Supplementary Material online).

机译：热敏蛋白瞬时受体潜在阳离子通道亚家族A的成员1（TRPA1）在低于17℃的温度下被多种试剂激活，包括异硫氰酸烯丙酯和肉桂醛（Dhaka等，2006）。最近，报道了TRPA1在人表皮中的表达（Atoyan等，2009）。因此，表皮角质形成细胞可能具有对低温有反应的感觉系统。为了验证该想法，我们检查了低温和调节TRPA1的试剂对培养的人角膜核细胞的细胞内钙水平的影响（有关详细信息，请参见在线补充材料中的方法）。

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《The Journal of investigative dermatology.》 |2010年第7期|共4页
作者
Tsutsumi M; Denda S; Ikeyama K; Goto M; Denda M;
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中图分类皮肤病学与性病学;
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1. Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes. [J] . Tsutsumi M, Denda S, Ikeyama K, The Journal of investigative dermatology. . 2010,第7期

机译：暴露于低温下会诱导培养的人角质形成细胞中细胞内钙的升高。
2. Effect of intracellular calcium modulation on sulfur mustard cytotoxicity in cultured human neonatal keratinocytes. [J] . Sawyer TW, Hamilton MG Toxicology in vitro: an international journal published in association with BIBRA . 2000,第2期

机译：细胞内钙调制对培养的人新生儿角质形成细胞中硫芥菜细胞毒性的影响。
3. Intracellular calcium elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15 neuronal cells with or without exogenous expression of human oxytocin receptors. [J] . Amina S, Hashii M, Ma WJ, Journal of neuroendocrinology . 2010,第5期

机译：在有或没有外源表达人催产素受体的啮齿动物NG108-15神经元细胞中，通过细胞外施用环状ADP-核糖或催产素诱导的细胞内钙升高对温度敏感。
4. Effects of Low-Level Laser Exposure on Calcium Channels and Intracellular Release in Cultured Astrocytes [C] . Thomas S Mang, Mohammed Mehdi Maneshi, David Wm. Shucard, Mechanisms of photobiomodulation therapy XI . 2016

机译：低水平激光照射对培养的星形胶质细胞钙通道和细胞内释放的影响
5. Intracellular calcium dynamics in traumatic brain injury: Understanding the role of N-type voltage-gated calcium channels in stretch-induced calcium rise in cortical neurons. [D] . Shahlaie, Kiarash. 2006

机译：在颅脑外伤中的细胞内钙动力学：了解N型电压门控钙通道在皮层神经元拉伸诱导的钙升高中的作用。
6. Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in J774 macrophages exposed to low and to high concentrations of endotoxin. [O] . R Korhonen, H Kankaanranta, A Lahti, 2001

机译：细胞内钙升高对暴露于低浓度和高浓度内毒素的J774巨噬细胞中可诱导型一氧化氮合酶表达的双向影响。
7. Exposure to Low Temperature Induces Elevation of Intracellular Calcium in Cultured Human Keratinocytes [O] . Tsutsumi Moe, Denda Sumiko, Ikeyama Kazuyuki, 2010

机译：暴露于低温下会诱导培养的人类角质形成细胞内细胞内钙的升高

Exposure to low temperature induces elevation of intracellular calcium in cultured human keratinocytes.

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