...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of laryngology and otology. >Potential roles of stem cells in the management of sensorineural hearing loss
【24h】

Potential roles of stem cells in the management of sensorineural hearing loss

机译：干细胞在感觉神经性听力损失管理中的潜在作用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: In the management of sensorineural hearing loss, effective therapy for degenerated hair cells, third order neurons, ganglions, dendrites and synaptic areas of the vestibulo-cochleo-cerebral pathway remains an enigma. Transplantation of stem and progenitor cells appears to be an emerging potential solution, and is the focus of this review.Aim: To review recent developments in the management of sensorineural hearing loss in the field of stem cell research.Materials and method: A systematic review of the English language literature included all experimental and non-experimental studies with a Jadad score of three or more, published between 2000 and 2010 and included in the following databases: Cochrane Library Ear, Nose and Throat Disorders; Medline; Google Scholar; Hinari; and the Online Library of Toronto University.Results: Of the 455 and 29 600 articles identified from Medline and Google Scholar, respectively, 48 met the inclusion criteria. These were independently reviewed and jointly analysed.Conclusion: Although there is not yet any evidence from successful human studies, stem cell and 'alternative stem cell' technology seems to represent the future of sensorineural hearing loss management.
机译：背景：在感觉神经性听力损失的管理中，对前庭-耳蜗-脑通路的退化的毛细胞，三阶神经元，神经节，树突和突触区域的有效疗法仍然是一个谜。干细胞和祖细胞的移植似乎是一种新兴的潜在解决方案，也是本综述的重点。目的：综述干细胞研究领域感音神经性听力损失管理的最新进展材料和方法：系统综述在英语文献中，Jadad得分在3或以上的所有实验和非实验研究均于2000年至2010年之间发表，并纳入以下数据库：Cochrane图书馆的耳朵，鼻子和喉咙疾病; Medline;谷歌学术; Hinari;结果：从Medline和Google Scholar分别确定的455和29 600篇文章中，有48篇符合纳入标准。结论：尽管尚无成功的人体研究证据，但干细胞和“替代干细胞”技术似乎代表了感音神经性听力损失管理的未来。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号