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首页> 外文期刊>The Journal of Nervous and Mental Disease >Gender differences in bipolar disorder type 1: a 48-week prospective follow-up of 72 patients treated in an italian tertiary care center.
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Gender differences in bipolar disorder type 1: a 48-week prospective follow-up of 72 patients treated in an italian tertiary care center.

机译：1型双相情感障碍的性别差异：在意大利三级医疗中心接受治疗的72名患者的48周前瞻性随访。

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摘要

To explore gender differences in bipolar I disorder, we compared the longitudinal treatment outcome and baseline demographic and clinical characteristics of 27 male and 45 female adult subjects who were treated for an acute affective episode and longitudinally followed for a period of up to 48 weeks. Females were more likely to report a history of suicidal gestures and a comorbid panic disorder; males were more likely to present with a comorbid obsessive-compulsive disorder, and there was a trend for a more frequent history of alcohol or substance abuse. No significant differences were found between the genders for the time to remission from the index episode, number of recurrences, and time spent with any clinical or subclinical mood symptom during the 48 weeks of maintenance treatment. Although differences may exist between bipolar I male and female subjects, prospective course does not seem to reveal differences in a 48-week period, at least when similar treatment strategies are adopted.
机译：为了探讨双相I型障碍的性别差异，我们比较了接受急性情感发作并纵向随访长达48周的27名男性和45名女性成人受试者的纵向治疗结果以及基线人口统计学和临床​​特征。女性更有可能报告有自杀手势和并发恐慌症的病史。男性更容易出现合并性强迫症，而且有酗酒或滥用药物史的趋势。在维持治疗的48周期间，从症状发作缓解的时间，复发的次数以及任何临床或亚临床情绪症状所花费的时间之间，性别之间没有发现显着差异。尽管双相I型男性和女性受试者之间可能存在差异，但至少在采用类似治疗策略的情况下，前瞻性疗程似乎在48周内未显示出差异。

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