Vulnerability in clinical research with patients in pain: a risk analysis.

Tait RC

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Vulnerability in clinical research with patients in pain: a risk analysis.

机译：疼痛患者在临床研究中的脆弱性：风险分析。

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Some have characterized patients living with intractable pain as a vulnerable population in both clinical and research settings. Labeling the population as vulnerable, however, does not provide clarity regarding the potential risks that they face when they participate in research. Instead, research vulnerability for patients in pain is a function of an interaction between their pain conditions and elements of the research enterprise. Therefore, the identification of potential risks requires consideration not only of characteristics of patients with chronic pain, but also consideration of features of researchers, the quality of institutional oversight, and the medical/social environment within which the research is conducted. This paper provides an analysis of those risks and provides some suggestions as to how the risks might be better managed.

机译：在临床和研究环境中，有些人将患有顽固性疼痛的患者描述为脆弱人群。但是，将人群标记为易受伤害人群并不能明确说明他们参与研究时面临的潜在风险。取而代之的是，疼痛患者的研究脆弱性是患者疼痛状况与研究企业要素之间相互作用的函数。因此，潜在风险的识别不仅需要考虑慢性疼痛患者的特征，还需要考虑研究人员的特征，机构监督的质量以及进行研究的医学/社会环境。本文对这些风险进行了分析，并就如何更好地管理风险提供了一些建议。

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《The Journal of law, medicine & ethics: a journal of the American Society of Law, Medicine & Ethics》 |2009年第1期|共14页
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Tait RC;
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中图分类医学伦理学;
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Vulnerability in clinical research with patients in pain: a risk analysis.

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