...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Neuroscience: The Official Journal of the Society for Neuroscience >Reorganization in primary motor cortex of primates with long-standing therapeutic amputations.
【24h】

Reorganization in primary motor cortex of primates with long-standing therapeutic amputations.

机译：长期治疗性截肢的灵长类动物原发性运动皮层的重组。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Intracortical microstimulation was used to investigate the organization of primate primary motor cortex (M1) in three squirrel monkeys and two galagos years after the therapeutic amputation of an injured forelimb or hindlimb. In two squirrel monkeys with forelimb amputation, physiological results were correlated with the distribution of corticospinal neurons after injections of tracers into the lower cervical segments of the spinal cord. Distributions of labeled corticospinal neurons helped identify the locations of the former forelimb cortex in M1. Evoked movements from M1 ipsilateral to the missing limb were not obviously different from M1 of normal controls. Stimulation in the deefferented part of M1 contralateral to the missing limb elicited movements of the remaining proximal muscles as well as movements from adjacent body representations in all cases. Stimulation in the deefferented forelimb cortex evoked shoulder stump, trunk, and orofacial movements, whereas stimulation in the deefferented hindlimb cortex evoked hip stump, trunk, and tail movements. Movements were evoked from all sites in the deprived cortex, so that there were no unresponsive zones. Minimal levels of current necessary to evoke these movements varied from those in the normal range to those of much higher levels, with the average threshold higher than normal. Finally, multiunit recording from the two galagos revealed that the deprived portions of S1 were responsive to touch or taps on the stump and neighboring body parts.
机译：皮层内微刺激用于调查在治疗性截肢受伤的前肢或后肢后的三只松鼠猴和两个加拉戈年的灵长类动物初级运动皮层（M1）的组织。在两只前肢截肢的松鼠猴中，将示踪剂注射到脊髓的下颈段后，其生理结果与皮质脊髓神经元的分布相关。标记的皮质脊髓神经元的分布有助于确定M1中前前皮质的位置。从M1同侧到缺肢的诱发运动与正常对照组的M1并无明显差异。在所有情况下，在缺少肢体的对侧M1的出射部分中进行刺激都会引起其余近端肌肉的运动以及邻近身体的运动。在脱气的前肢皮质刺激会引起肩膀残端，躯干和口面部运动，而在脱气的后肢皮质刺激则会引起髋部残端，躯干和尾巴运动。剥夺皮层中所有部位均引起运动，因此没有无反应区。引起这些运动所需的最小电流水平从正常范围的电流变化到更高水平的电流，平均阈值高于正常水平。最后，来自两个加拉各斯的多单位记录显示，S1的被剥夺部分对树桩和邻近身体部位的触摸或轻拍做出了响应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号