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A poke into the diversity and associations within human anterior nare microbial communities

机译:探究人类前鼻孔微生物群落中的多样性和关联性

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The anterior nares are the major reservoir for Staphylococcus aureus in humans, where nasal carriage has a crucial function as a source for invasive infections. Despite various investigations on aerobic community members based on traditional cultivation methods, little is known on the overall microbial composition and complex in situ interactions, but such knowledge is highly warranted for effective S. aureus control strategies. As assessed using advanced culture-independent approaches, this study provides a comprehensive survey of the anterior nare bacterial community of 40 individuals. Previously undiscovered co-colonization patterns and natural variations in species composition were revealed and provide insights for future intervention strategies for the control of health-care- and community-associated S. aureus infections.
机译:前鼻孔是人类金黄色葡萄球菌的主要贮藏库,其中鼻腔运输作为侵入性感染的来源具有至关重要的作用。尽管对基于传统耕种方法的有氧社区成员进行了各种调查,但对整体微生物组成和复杂的原位相互作用了解甚少,但是对于有效的金黄色葡萄球菌控制策略而言,此类知识是非常必要的。如使用先进的独立于培养的方法评估,本研究对40个个体的前鼻孔细菌群落进行了全面调查。揭示了以前未发现的共殖模式和物种组成的自然变化,并为控制健康和社区相关的金黄色葡萄球菌感染的未来干预策略提供了见识。

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