Risk for Osteoporosis and Antiresorptive Therapies in Patients with Crohn's Disease

Josette Makhzoum; Gilles Jobin; Pierre Dagenais; Sylvie Makhzoum; Sylvie Perreault

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Risk for Osteoporosis and Antiresorptive Therapies in Patients with Crohn's Disease

机译：克罗恩病患者发生骨质疏松症和抗再吸收疗法的风险

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Background: The risk of osteoporosis is greater in patients with inflammatory bowel disease (IBD) because of several related risk factors such as the prolonged use of corticosteroids, the malabsorption of calcium and vitamin D following small-bowel disease or small-bowel resections, and the inflammatory process resulting from the illness. A reduction in bone mineral density (BMD) has been reported in 30-75% of patients with IBD (Crohn's disease or ulcerative colitis). An evaluation of the risk factors of osteoporosis should be performed to identify those in need of antiresorptive drug therapies (ART) and /or calcium and vitamin D supplements.

机译：背景：炎性肠病（IBD）患者的骨质疏松症风险较高，原因是有几个相关的危险因素，例如长期使用皮质类固醇，小肠疾病或小肠切除术后钙和维生素D吸收不良，以及由疾病引起的炎症过程。据报道，IBD（克罗恩病或溃疡性结肠炎）患者中有30-75％的人的骨矿物质密度（BMD）降低。应该对骨质疏松症的危险因素进行评估，以确定需要抗吸收药物疗法（ART）和/或钙和维生素D补充剂的人。

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《The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians》 |2006年第1期|共6页
作者
Josette Makhzoum; Gilles Jobin; Pierre Dagenais; Sylvie Makhzoum; Sylvie Perreault;
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1. Risk for Osteoporosis and Antiresorptive Therapies in Patients with Crohn's Disease [J] . Josette Makhzoum, Gilles Jobin, Pierre Dagenais, The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians . 2006,第1期

机译：克罗恩病患者发生骨质疏松症和抗再吸收疗法的风险
2. Re-evaluating osteoporosis and fracture risk in Crohn's disease patients in the era of TNF-alpha inhibitors [J] . Hakimian Shahrad, Kheder Joan, Arum Seth, Scandinavian journal of gastroenterology. . 2018,第2期

机译：在TNF-α抑制剂时代重新评估克罗恩病患者骨质疏松症和骨折风险
3. Postoperative Morbidity Risks Following Ileocolic Resection for Crohn's Disease Treated With Anti-TNF Alpha Therapy: A Retrospective Study of 360 Patients [J] . Jouvin Ingrid, Lefevre Jeremie H., Creavin Ben, Inflammatory bowel diseases . 2018,第2期

机译：术后发病率风险后对抗TNFα治疗治疗的CROHN病疾病术后：360例患者的回顾性研究
4. Antiresorptive effect of denosumab in the treatment of osteoporosis in patients with rheumatoid arthritis [C] . M. A. Korolev, N. E. Banshchikova, E. A. Letjagina, 2017 International Multi-Conference on Engineering, Computer and Information Sciences . 2017

机译：地诺单抗对类风湿关节炎骨质疏松症的抗吸收作用
5. Yoga as an adjunctive therapy for Crohn's disease: A review of the effects of exercise and stress reduction on the quality of life and disease progression in Crohn's disease patients. [D] . Zuckerman, Julie. 2012

机译：瑜伽作为克罗恩氏病的辅助疗法：运动和减轻压力对克罗恩氏病患者生活质量和疾病进展的影响综述。
6. Prevalence Risk Factors and Course of Osteoporosis in Patients with Crohn’s Disease at a Tertiary Referral Center [O] . Peter Hoffmann, Johannes Krisam, Christian Kasperk, 2019

机译：三级转诊中心克罗恩病患者的骨质疏松患病率危险因素和病程
7. Prevalence, Risk Factors and Course of Osteoporosis in Patients with Crohn’s Disease at a Tertiary Referral Center [O] . Peter Hoffmann, Johannes Krisam, Christian Kasperk, 2019

机译：第三节推荐中心克罗恩病患者患者患者患病率，危险因素和骨质疏松症

Risk for Osteoporosis and Antiresorptive Therapies in Patients with Crohn's Disease

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