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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Iron Supplementation and Epoetin Alfa in a Jehovah's Witness with Severe Iron Deficiency Anemia
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Iron Supplementation and Epoetin Alfa in a Jehovah's Witness with Severe Iron Deficiency Anemia

机译：耶和华见证人患有严重缺铁性贫血的补铁和依泊汀阿尔法

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Objective: To report a case of severe iron deficiency anemia (IDA) in a Jehovah's Witness, successfully treated with iron supplementation and epoetin alfa.Case Summary: A 69-year-old African man, a Jehovah's Witness, presented with severe IDA of unknown cause and was admitted to the general medicine service. He was treated with oral and intravenous iron and subcutaneous epoetin alf a. His serum hemoglobin concentration steadily improved. He was discharged to home on epoetin alia and iron supplementation. His hemoglobin concentration was stable 1 month later.Discussion: Iron is a critical factor in hemoglobin synthesis and erythropoiesis, and iron deficiency is a common cause of anemia. Jehovah's Witnesses with severe anemia pose a challenge to providers because of their refusal to accept blood products. Alternative treatment regimens are few, and little evidence exists to guide treatment decisions. Recombinant human erythropoietin (rHuEpo) may play a role, but little is known about its use in IDA. Most studies on rHuEpo focus on its use in the setting of surgery, burns, trauma, pregnancy, and severe gastrointestinal bleeding.Conclusions: This case demonstrates that rHuEpo plus iron supplementation may be an acceptable alternative to blood transfusion in a Jehovah's Witness patient with severe IDA.
机译：目的：报道一例耶和华见证人严重缺铁性贫血（IDA）并成功补充铁和艾泊汀阿尔法的病例。病例总结：一名69岁的非洲男子耶和华见证人，表现为重度IDA不明原因，并被录入普通医学服务。他曾接受口服和静脉注射铁剂以及皮下的艾泊汀alf a治疗。他的血红蛋白浓度稳定提高。他因促胰岛素和补充铁而出院。 1个月后他的血红蛋白浓度稳定。讨论：铁是血红蛋白合成和红细胞生成的关键因素，铁缺乏是贫血的常见原因。患有严重贫血的耶和华见证人由于拒绝接受血液制品而给医疗服务提供者带来了挑战。替代治疗方案很少，几乎没有证据可以指导治疗决策。重组人促红细胞生成素（rHuEpo）可能起作用，但对其在IDA中的用途知之甚少。关于rHuEpo的大多数研究都集中在其在外科手术，烧伤，创伤，妊娠和严重胃肠道出血中的应用。结论：该案例表明，rHuEpo加铁补充剂可能是耶和华见证人重症患者输血的一种可接受的替代方法。 IDA。

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