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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Evaluation of Anticoagulation Management and Chronic Disease State Control in a Pharmacist-Run Pharmacotherapy/ Anticoagulation Clinic
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Evaluation of Anticoagulation Management and Chronic Disease State Control in a Pharmacist-Run Pharmacotherapy/ Anticoagulation Clinic

机译：在药剂师经营的药物治疗/抗凝临床中评估抗凝管理和慢性病状态

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Background: The benefit of pharmacist-run clinics for anticoagulation, dyslipidemia, diabetes, and hypertension has been described in the literature as individual services. We describe a clinic model in which anticoagulation and other chronic disease states are managed concomitantly.Objective: To evaluate the control of anticoagulation, hypertension, dyslipidemia, and diabetes in anticoagulation patients enrolled in a pharmacotherapy / anticoagulation clinic.Methods: Patients seen in the pharmacotherapy/anticoagulation clinic for management of anticoagulation were included in a retrospective review. Demographic information, blood pressure measurements, and laboratory values were recorded. Initial and final results were compared and statistically analyzed. Benchmark goals were set for each parameter analyzed.Results: Between August 2007 and July 2008,282 patients were enrolled in the clinic. While slightly increasing the average time in therapeutic range from 69.9% to 70.7%, the clinical pharmacists also managed hypertension, dyslipidemia, and diabetes, if present. Systolic (p = 0.0075; 95% CI 0.98 to 6.31) and diastolic (p = 0.004; 95% CI 1.26 to 4.33) blood pressures decreased during the study period such that the number of patients with controlled blood pressure increased to 81%. Low-density lipoprotein cholesterol measurements decreased by an average of 5.9 mg/dL (p < 0.0001; 95% CI 3.121 to 8.789), with an increase in number of patients at goal to 86%. Although not significant, mean hemoglobin A_1c (A1C) values decreased an average of 0.12% (p = 0.1138; 95% CI 0.029 to 0.271), with an increase to 59% of those achieving a goal A1C.Conclusions: A pharmacotherapy /anticoagulation clinic can be considered a practice model for effective management of anticoagulation patients who require management of other chronic disease states.
机译：背景：药剂师开办的诊所对于抗凝，血脂异常，糖尿病和高血压的益处在文献中已被描述为个人服务。我们描述了一种可同时管理抗凝和其他慢性疾病状态的临床模型。目的：评估在药物疗法/抗凝诊所就诊的抗凝患者中抗凝，高血压，血脂异常和糖尿病的控制方法：在药物疗法中见过的患者回顾性审查中包括了用于抗凝治疗的/抗凝诊所。记录人口统计信息，血压测量值和实验室值。比较初始和最终结果并进行统计分析。结果：从2007年8月到2008年7月，共有282例患者入选该门诊。虽然平均治疗时间从69.9％略微增加到70.7％，但临床药剂师还应对了高血压，血脂异常和糖尿病（如果存在）。在研究期间，收缩压（p = 0.0075; 95％CI 0.98至6.31）和舒张压（p = 0.004; 95％CI 1.26至4.33）血压降低，因此血压可控的患者人数增加至81％。低密度脂蛋白胆固醇测量值平均下降5.9 mg / dL（p <0.0001; 95％CI 3.121至8.789），目标患者人数增加至86％。尽管并不显着，但平均血红蛋白A_1c（A1C）值平均降低了0.12％（p = 0.1138; 95％CI 0.029至0.271），达到目标A1C的患者增加了59％。结论：药物治疗/抗凝诊所可以被认为是有效管理需要其他慢性疾病状态治疗的抗凝患者的实践模型。

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