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Evaluation of the haemocompatibility of titanium based biomaterials

机译：钛基生物材料的血液相容性评估

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The increased use of metallic biomaterials in contact with blood e.g. for the application as coronary stents leads to the development of new biomaterials. The main requirements for stents are high flexibility, high cold deformability and sufficient mechanical strength (static and dynamic), which can be obtained by strain hardening, radio-opacity and haemocompatibility. In order to investigate the properties of the metallic biomaterials in contact with blood, a comparison of the haemocompatibility of newly developed materials with established materials has been performed. To evaluate haemocompatibility without the influence of the geometry of the materials, spherical powders produced by rotating electrode process (REP) were used in a dynamic test system with full human blood under two different stress conditions. The high shear stress simulates the arterial and the low shear stress simulates the venous situation. The use of a dimensionless score point (SP) system where the parameters of the haemocompatibility are determined with and without a material exposition allows an objective comparison of the materials used.
机译：金属生物材料与血液接触的使用增加，例如作为冠状动脉支架的应用导致了新的生物材料的发展。支架的主要要求是高柔韧性，高冷变形性和足够的机械强度（静态和动态），这可以通过应变硬化，不透射线和血液相容性获得。为了研究金属生物材料与血液接触的特性，已对新开发材料与已建立材料的血液相容性进行了比较。为了在不影响材料几何形状的情况下评估血液相容性，将旋转电极工艺（REP）产生的球形粉末用于动态测试系统中，该测试系统在两种不同的应力条件下对全人类血液进行了测试。高剪切应力模拟动脉，低剪切应力模拟静脉。使用无因次得分点（SP）系统，可以在有和没有材料暴露的情况下确定血液相容性参数，从而可以对所用材料进行客观比较。

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