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Commercial development of microalgal biotechnology: from the test tube to the marketplace

机译：微藻生物技术的商业开发：从试管到市场

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摘要

While humans have taken limited advantage of natural populations of microalgae for centuries (Nostoc in Asia and Spirulina in Africa and North America for sustenance), it is only recently that we have come to realize the potential of microalgal biotechnology. Microalgal biotechnology has the potential to produce a vast array of products including foodstuffs, industrial chemicals, compounds with therapeutic applications and bioremediation solution from a virtually untapped source. From an industrial (i.e. commercial) perspective, the goal of microalgal biotechnology is to make money by developing marketable products. For such a business to succeed the following steps must be taken: identify a desirable metabolite and a microalga that produces and accumulates the desired metabolite, establish a large-scale production process for the desired metabolite, and market the desired metabolite. So far, the commercial achievements of microalgal biotechnology have been modest. Microalgae that produce dozens of desirable metabolites have been identified. Aided by high throughput screening technology even more leads will become available. However, the successes in large-scale production and product marketing have been few. We will discuss those achievements and difficulties from the industrial point of view by considering examples from industry, specially our own experience at Mera Pharmaceuticals.
机译：尽管数百年来人类一直在利用微藻自然种群的有限优势（亚洲的Nostoc和非洲和北美的螺旋藻用于维持生计），但直到最近，我们才意识到微藻生物技术的潜力。微藻生物技术有潜力从几乎未开发的资源中生产各种产品，包括食品，工业化学品，具有治疗用途的化合物和生物修复解决方案。从工业（即商业）的角度来看，微藻生物技术的目标是通过开发适销对路的产品来赚钱。为了使这种业务成功，必须采取以下步骤：识别所需的代谢物和产生并积累所需代谢物的微藻，建立所需代谢物的大规模生产工艺，并销售所需代谢物。到目前为止，微藻生物技术的商业成就还很薄弱。已经鉴定出产生数十种所需代谢产物的微藻。在高通量筛选技术的帮助下，将有更多的潜在客户。但是，在大规模生产和产品营销方面的成功很少。我们将通过行业实例，特别是我们在Mera Pharmaceuticals的经验，从行业角度讨论这些成就和困难。

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