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首页> 外文期刊>Chromosoma >Chromosome synapsis in Arabidopsis: analysis of the transverse filament protein ZYP1 reveals novel functions for the synaptonemal complex.
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Chromosome synapsis in Arabidopsis: analysis of the transverse filament protein ZYP1 reveals novel functions for the synaptonemal complex.

机译:拟南芥中的染色体突触:横向细丝蛋白ZYP1的分析揭示了突触复合物的新功能。

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摘要

With respect to history, plants have provided an ideal system for cytogenetical analysis of the synaptonemal complex (SC). However, until recently, the identification of the genes that encode the SC in plants has proved elusive. In recent years, Arabidopsis thaliana was developed as a model system for plant meiosis research. As a result, there was substantial progress in the isolation of meiotic genes and this has recently led to the isolation of the first plant SC gene, ZYP1. The ZYP1 gene encodes a transverse filament (TF) protein that is predicted to have structural similarity to TF proteins found in other organisms. Analysis of plants deficient in ZYP1 expression has provided important insights into the function of the SC in plants. Loss of ZYP1 has only a limited effect on the overall level of recombination. However, it is associated with extensive nonhomologous recombination leading to multivalent formation at metaphase I. This phenomenon was not previously reported in other organisms. It is important to note that cytological analysis of the ZYP1 deficient lines indicates that SC formation is not required for the imposition of crossover interference.
机译:就历史而言,植物为突触复合物(SC)的细胞遗传学分析提供了理想的系统。然而,直到最近,证明编码植物中SC的基因的鉴定还难以实现。近年来,拟南芥被开发为用于植物减数分裂研究的模型系统。结果,减数分裂基因的分离取得了实质性进展,最近这导致了第一个植物SC基因ZYP1的分离。 ZYP1基因编码横向丝(TF)蛋白,该蛋白预计与在其他生物中发现的TF蛋白具有结构相似性。对ZYP1表达不足的植物的分析为SC在植物中的功能提供了重要的见识。 ZYP1的损失仅对整体重组水平产生有限的影响。但是,它与广泛的非同源重组相关,导致在中期I形成多价。这种现象以前没有在其他生物中报道过。重要的是要注意,对ZYP1缺陷株系的细胞学分析表明,对交叉干扰施加不需要SC的形成。

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