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Compositional dependence of in-vitro bioactivity in sodium calcium borate glasses

机译:硼酸钠钙玻璃体外生物活性的成分依赖性

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Borate glasses with composition xCaO (100-x) B_2O_3 (20≤x≤50), where x is in mole percent) and 50CaO·45B_2O_3·5Na_O have been prepared using conventional melt quench technique. Samples were submerged in simulating body fluid solution (SBF) at 37 °C for various periods of time. After storage the samples were analyzed in order to investigate if a surface layer of hydroxyl carbonate apatite layer (HCA layer/Ca-P layer) had formed. The analysis technique used included Fourier-Transform Infrared Spectroscopy (FTIR). The rate of HCA layer formation on the surface of exposed glass samples is determined by FTIR, percentage weight loss measurements of glass samples in SBF and variation of pH of SBF as a function of time. Increase in calcium content in the glass matrix has shown to decrease the rate of HCA formation on glass surfaces. The borate glass with x=20 has shown HCA layer formation on glass surface within two days of dipping. The bone like apatite formation of glass surface demonstrates the potential of glass for integration with bone.
机译:已经使用常规的熔融淬火技术制备了组成为xCaO(100-x)B_2O_3(20≤x≤50),其中x为摩尔百分比)和50CaO·45B_2O_3·5Na_O的硼酸盐玻璃。将样品浸入37°C的模拟体液溶液(SBF)中不同时间。储存后,分析样品以调查是否已形成碳酸羟基磷灰石层的表面层(HCA层/ Ca-P层)。所使用的分析技术包括傅里叶变换红外光谱(FTIR)。通过FTIR,SBF中玻璃样品的重量损失百分比测量以及SBF的pH随时间的变化来确定暴露的玻璃样品表面上HCA层的形成速率。玻璃基质中钙含量的增加已表明减少了玻璃表面上HCA的形成速率。 x = 20的硼酸盐玻璃在浸入后的两天内显示出在玻璃表面上形成了HCA层。玻璃表面的骨状磷灰石形成表明玻璃具有与骨整合的潜力。

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