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首页> 外文期刊>The Journal of Prosthetic Dentistry >Dental extractions after radiation therapy in the head and neck area and hard tissue replacement (HTR) therapy: a preliminary study.
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Dental extractions after radiation therapy in the head and neck area and hard tissue replacement (HTR) therapy: a preliminary study.

机译：头颈部区域放射治疗和硬组织替代（HTR）治疗后的牙齿摘除：初步研究。

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STATEMENT OF PROBLEM: Dental extractions in patients who had radiation therapy for cancer in the head and neck region carry with them the risks of delayed healing, prolonged alveolar bone exposure, infection, and osteoradionecrosis. Among the precautions to minimize these risks are antibiotic coverage, limited extractions at any one time, soft tissue closure, and hyperbaric oxygen treatment. Rapid epithelization and minimal bone exposure are essential after extractions in irradiated patients. PURPOSE: This study examined the effects of hard tissue replacement on head and neck cancer patients who were treated with radiation therapy. MATERIAL AND METHODS: In a series of eight patients who had radiation doses from 4000 cGy to 7440 cGy in the head and neck area and who had 44 teeth extracted, hard tissue replacement material mixed with tetracycline powder was placed in the extraction sites. RESULTS: Of the 44 teeth extracted, 19 mandibular molars and premolars were in the direct field of radiation in seven patients. One patient also had 6 mandibular anterior teeth and 12 maxillary teeth extracted that received minimal radiation exposure. One patient had 6 mandibular anterior teeth extracted that were not in the area of direct exposure. One patient had a mandibular first molar extracted in an area that received minimal radiation exposure. Clinically, complete epithelization occurred in all patients. No infections developed. Radiographically no bone dissolution could be identified in the extraction area(s). The follow-up times ranged from 7 months to 18 months when the patients were seen last. CONCLUSION: The hard tissue replacement particles appears to provide a matrix for fibrous connective tissue formation.
机译：问题陈述：在头颈部区域接受过癌症放射治疗的患者中，拔牙可能会导致延迟愈合，牙槽骨暴露时间长，感染和骨放射性坏死的风险。使这些风险最小化的预防措施包括抗生素覆盖，任何时间限制提取，软组织封闭和高压氧治疗。在接受辐射的患者拔除后，快速上皮化和最小限度的骨骼暴露至关重要。目的：本研究检查了硬组织置换对接受放射治疗的头颈癌患者的影响。材料与方法：在八名患者的头颈部区域放射剂量为4000 cGy至7440 cGy，并拔出44颗牙齿的一系列患者中，将混合有四环素粉的硬组织替代材料放置在拔牙部位。结果：在拔出的44颗牙齿中，有7例患者的放射线直接照射了19颗下颌磨牙和前磨牙。一名患者还接受了6颗下颌前牙和12颗上颌牙的放射线照射。 1例患者的6颗下颌前牙不在直接暴露区域。一名患者的下颌第一磨牙在受到最小辐射照射的区域拔出。临床上，所有患者均发生完全上皮化。没有感染发生。放射学上在提取区域未发现骨溶解。随访时间从7个月到18个月不等。结论：硬组织替代颗粒似乎为纤维结缔组织形成提供了基质。

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