首页> 外文期刊>The Journal of Prosthetic Dentistry >Health-related quality of life in patients with sleep-disordered breathing: effect of mandibular advancement appliances.
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Health-related quality of life in patients with sleep-disordered breathing: effect of mandibular advancement appliances.

机译:睡眠呼吸障碍患者的健康相关生活质量:下颌前移矫正器的作用。

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STATEMENT OF PROBLEM: Mandibular advancement appliances (MAAs) are increasingly being recognized in the management of sleep-disordered breathing (SDB). However, there is little available evidence regarding their impact on health-related quality of life. PURPOSE: A prospective, nonrandomized controlled clinical trial was undertaken to evaluate the effect of MAA treatment on the quality of life of patients with SDB. MATERIAL AND METHODS: Two hundred fifteen consecutively referred patients for MAA therapy who had a diagnosis of SDB confirmed by overnight polysomnography were recruited for study. The test group (n=120) received a Herbst appliance, a removable appliance comprised of separate maxillary and mandibular complete occlusal coverage acrylic splints, connected by means of bilateral telescopic arms. Patients in the control group (n=95) remained untreated for 4 months. All patients completed the Medical Outcomes Study 36-Item Short-Form Health Survey at baseline (T1) and at follow-up (T2). Cross-tabulation was performed for each independent variable against the group (control versus test) to determine the number of subjects and the percentage showing improvement and the level of significance (alpha=.05). Data were dichotomized (improvement versus no improvement), analyzed by simple logistic regression analysis, and expressed as the odds ratio. RESULTS: Eighty-three (87%) control and 107 (89%) test patients completed the study. No statistical differences were observed at baseline in any of the parameters relating to severity of SDB, demographic, anthropometric, or quality of life measures between the 2 groups. Significant differences were observed in relation to the energy/vitality (P=.001) and physical role limitation (P=.025) domains following 4 months of treatment with an MAA. CONCLUSIONS: Mandibular advancement appliances have a significant effect on a limited number of health-related quality of life domains for patients with SDB.
机译:问题陈述:在睡眠呼吸障碍(SDB)的管理中,人们越来越认识到下颌前移矫正器(MAA)。但是,关于它们对与健康相关的生活质量的影响的可用证据很少。目的:进行一项前瞻性,非随机对照临床试验,以评估MAA治疗对SDB患者生活质量的影响。材料与方法:招募了215位连续转诊的接受MAA治疗的患者,这些患者经通宵多导睡眠图检查确诊为SDB,并进行了研究。测试组(n = 120)接受了Herbst矫治器,这是一种可拆除的矫治器,由独立的上颌和下颌完全遮盖性丙烯酸夹板组成,通过双侧伸缩臂连接。对照组(n = 95)患者未治疗4个月。所有患者均在基线(T1)和随访(T2)完成了医学成果研究36项简短形式健康调查。针对组中的每个独立变量(对照与测试)进行交叉制表,以确定受试者的数量以及显示改善和显着性水平的百分比(alpha = .05)。将数据分为两部分(改进与不改进),通过简单的逻辑回归分析进行分析,并表示为优势比。结果:八十三(87%)名对照和107名(89%)受试患者完成了研究。两组之间在与SDB的严重程度,人口统计学,人体测量学或生活质量测量有关的任何参数中,基线时均未观察到统计学差异。用MAA治疗4个月后,在能量/活力(P = .001)和身体角色限制(P = .025)域方面观察到显着差异。结论:下颌高级矫治器对SDB患者有限的健康相关生活质量域具有显着影响。

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