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首页> 外文期刊>The Journal of Urology >A prospective study of symptoms and quality of life in men with chronic prostatitis/chronic pelvic pain syndrome: the National Institutes of Health Chronic Prostatitis Cohort study.
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A prospective study of symptoms and quality of life in men with chronic prostatitis/chronic pelvic pain syndrome: the National Institutes of Health Chronic Prostatitis Cohort study.

机译：慢性前列腺炎/慢性盆腔疼痛综合征男性症状和生活质量的前瞻性研究：美国国立卫生研究院慢性前列腺炎队列研究。

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PURPOSE: We present the results of 2 years of symptom and quality of life followup of men with CP/CPPS enrolled in the CPC. MATERIALS AND METHODS: We followed 445 subjects from 6 clinical centers across North America for 2 years with outcome measures that included the NIH-CPSI, quality of life, and GRA. All subjects were treated according to usual care practices at each clinical site. RESULTS: Of the 445 subjects 293 had complete data at 2 years. Withdrawals were younger, had been diagnosed more recently and had higher baseline symptoms. Among the 293 men the mean improvement at 2 years was 5 points on the 43-point NIH-CPSI total score. Most of the observed improvement occurred in the first 3 months of followup. Among all 445 subjects, retaining withdrawals in the denominator, 31% considered themselves moderately or markedly improved at 2 years. Although group mean symptom scores were stable and improved slightly over time, some individual subjects reported large fluctuations. No baseline demographic or clinical factors significantly predicted changes in symptom scores over time. CONCLUSIONS: CP/CPPS is a chronic disease characterized by substantial variation in symptoms within and among subjects. There is no evidence that the disorder worsens significantly during 2 years of followup, and for about a third of men with long-standing symptoms there may be moderate to marked improvement during this period.
机译：目的：我们介绍了参加CP的CP / CPPS男性2年的症状和生活质量随访结果。材料和方法：我们追踪了北美6个临床中心的445名受试者，历时2年，其结果包括NIH-CPSI，生活质量和GRA。根据每个临床部位的常规护理实践对所有受试者进行治疗。结果：445名受试者中有293名在2年时有完整的数据。戒断较年轻，被诊断出较新且基线症状较高。在293名男性中，2年平均改善43分的NIH-CPSI总得分为5分。观察到的大多数改善都发生在随访的前3个月。在所有445名受试者中，保留分母的退出者中，有31％认为自己在2年时有中度或明显改善。尽管组平均症状评分稳定且随时间推移略有改善，但一些个体受试者报告波动较大。没有基线人口统计学或临床因素能显着预测症状分数随时间的变化。结论：CP / CPPS是一种慢性疾病，其特征在于受试者内部和受试者之间的症状有很大的变化。没有证据表明该疾病在随访的2年中会明显恶化，对于约有长期症状的男性，在此期间可能会有中度到明显的改善。

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