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首页> 外文期刊>The journal of sexual medicine >Beneficial impact of exercise and obesity interventions on erectile function and its risk factors.
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Beneficial impact of exercise and obesity interventions on erectile function and its risk factors.

机译：运动和肥胖干预对勃起功能及其危险因素的有益影响。

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INTRODUCTION: Erectile dysfunction (ED) is a multifaceted disease involving cardiovascular, metabolic, and hormonal factors and affects over 100 million men worldwide. ED has been shown to be a harbinger of underlying cardiovascular diseases (CVD), as there are common risk factors (aging, hypertension, obesity) and mechanistic basis. AIM: To provide an update on clinical and experimental evidence regarding the impact of lifestyle modifications, such as exercise and diet, with respect to changes in erectile function. MAIN OUTCOME MEASURES: Published evidence regarding the impact of aging, hypertension, and obesity on ED and CVD, as well as new experimental data linking obesity and diminished erectile responses. METHODS: We reviewed the literature regarding common risk factors of ED and CVD, particularly involving obesity, as well as performed new analysis on the findings of other experimental studies involving diet and exercise interventions. RESULTS: Physical inactivity negatively impacts on erectile function, and experimental and clinical exercise interventions have been shown to improve sexual responses and overall cardiovascular health. Mediterranean-style diets and a reduction in caloric intake have been found to improve erectile function in men with the aspects of the metabolic syndrome. In addition, both clinical and experimental studies have confirmed that combining the two interventions provides additional benefit to erectile function, likely via reduced metabolic disturbances (e.g., inflammatory markers, insulin resistance), decreased visceral adipose tissue, and improvement in vascular function (e.g., increased endothelial function). CONCLUSIONS: Lifestyle modifications provide significant benefits to vascular health and erectile function in a population that is increasingly aged and more obese.
机译：简介：勃起功能障碍（ED）是一种涉及心血管，代谢和激素因素的多方面疾病，影响全球1亿多男性。 ED已被证明是潜在的心血管疾病（CVD）的预兆，因为存在常见的风险因素（年龄，高血压，肥胖）和机制基础。目的：提供有关生活方式改变（如运动和饮食）对勃起功能变化影响的临床和实验证据的最新信息。主要观察指标：关于衰老，高血压和肥胖对ED和CVD的影响的公开证据，以及将肥胖与勃起反应减弱联系在一起的新实验数据。方法：我们回顾了有关ED和CVD常见危险因素的文献，特别是与肥胖有关的文献，并对包括饮食和运动干预在内的其他实验研究的结果进行了新的分析。结果：缺乏运动对勃起功能有负面影响，实验和临床运动干预措施已被证明可以改善性反应和总体心血管健康。已经发现，地中海式饮食和减少卡路里的摄入可以改善患有代谢综合征的男性的勃起功能。此外，临床和实验研究均已证实，将两种干预措施相结合可通过减少代谢紊乱（例如炎症标记，胰岛素抵抗），减少内脏脂肪组织和改善血管功能（例如，内皮功能增强）。结论：在日益老龄和肥胖的人群中，生活方式的改变可为血管健康和勃起功能带来重大好处。

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