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首页> 外文期刊>The journal of sexual medicine >Priapus is Happier with Venus than with Bacchus
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Priapus is Happier with Venus than with Bacchus

机译：Priapus对金星比对酒神更快乐

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Introduction. The relationship between alcohol consumption and erectile function is still not completely clarified. Aim. Aims of the present study are to explore a number of biological and clinical correlates of alcohol consumption in a sample of men consulting for sexual dysfunction, and to verify possible associations with the incidence of major adverse cardiovascular events (MACEs). Methods. A consecutive series of 1956 (mean age 55 +- 11.9 years old) attending our outpatient clinic for sexual dysfunction was retrospectively studied. A subset of the previous sample (N= 1687) was enrolled in a longitudinal study. Main Outcome Measures. Different clinical, biochemical, instrumental (penile Doppler ultrasound [PCDU]), and intrapsychic (Middlesex Hospital Questionnaire [MHQ]) were evaluated. We considered alcohol abuse more than three drinks per day. Results. Among the patients studied 81% reported no or mild (<4 drinks/day) alcohol consumption whereas 14.3% and 3.9% declared a moderate (4-6 drinks/day) or severe (>6 drinks/day) alcohol abuse, respectively. After adjustment for confounders, both moderate or severe alcohol abuse was associated with low perceived partner's sexual desire, worse couple relationship, and smoking abuse. Furthermore, moderate and severe alcohol abuse was associated with low prolactin and thyroid-stimulating hormone levels, as well as an increase in triglycerides and total cholesterol levels. Penile blood flow was reduced in moderate and severe alcohol drinkers even after adjustment for confounders. In the longitudinal study, after adjusting for confounding factors, any kind of alcohol abuse was independently associated with a higher incidence of MACE (hazard ratio = 2.043 [1.059-3.943]; P< 0.0001). Conclusions. Our findings demonstrate that, in subjects consulting for erectile dysfunction, severe alcohol consumption is associated with a worse sexual function and a higher incidence of MACE.
机译：介绍。饮酒与勃起功能之间的关系仍未完全阐明。目标。本研究的目的是在咨询性功能障碍的男性样本中探讨酒精摄入的许多生物学和临床相关性，并验证与主要不良心血管事件（MACE）发生率的可能关联。方法。回顾性研究了连续1956年（平均年龄55±11.9岁）在我们门诊就诊的性功能障碍患者。纵向研究中纳入了先前样本的一个子集（N = 1687）。主要观察指标。评估了不同的临床，生化，仪器（阴茎多普勒超声[PCDU]）和精神内（Middlesex医院问卷[MHQ]）。我们认为酒精滥用每天超过三种饮料。结果。在接受研究的患者中，有81％的人表示没有或轻微（<4杯/天）饮酒，而14.3％和3.9％的人分别宣布中度（4-6杯/天）或严重（> 6杯/天）饮酒。在对混杂因素进行调整之后，中度或重度酗酒都与感知到的伴侣的性欲低下，夫妻关系恶化和吸烟有关。此外，中度和重度酒精滥用与催乳激素和促甲状腺激素水平低以及甘油三酸酯和总胆固醇水平升高有关。即使调整了混杂因素，中度和重度饮酒者的阴茎血流量也减少了。在纵向研究中，在调整混杂因素后，任何种类的酒精滥用都与MACE发生率升高独立相关（危险比= 2.043 [1.059-3.943]; P <0.0001）。结论。我们的发现表明，在咨询勃起功能障碍的受试者中，严重饮酒与性功能较差和MACE发生率较高相关。

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