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Postorgasm illness syndrome--a spectrum of illnesses.

机译:高潮后疾病综合症-一系列疾病。

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INTRODUCTION: We describe two men with marked symptoms following orgasm. In each case, the symptoms were consistent with those found in postorgasm illness syndrome (POIS). AIM: Further elucidation of the cause of the patients' symptoms. METHODS: Both cases were investigated for causes of POIS with biochemical, hormonal, neurological, autonomic, cardiological, and psychological workup. RESULTS: Extensive investigation did not reveal a major organic cause for these patients' symptoms. Detailed history revealed likely differing etiologies in each case. In one case, the symptom picture suggested cytokine release, and, in fact, the patient subjectively improved by 80% on taking nonsteroidal anti-inflammatory drugs just prior to and for a day or two after orgasm. The other case appeared to have an ethnic/cultural etiology that was associated with the "Dhat" syndrome. CONCLUSION: The apparent differing etiologies/clinical associations of these cases highlight the need for careful history, examination, and investigations in patients presenting with POIS. We recommend that each case needs individual consideration and investigation, and treatment needs to be tailored to the likely cause. It seems likely that POIS represents a spectrum of syndromes of differing etiologies. Further research into the neurobiochemical sequelae of orgasm will be useful in understanding the pathological processes in these cases.
机译:简介:我们描述了两名高潮后有明显症状的男人。在每种情况下,症状与高潮后综合症(POIS)中发现的症状一致。目的:进一步阐明患者症状的原因。方法:通过生化,激素,神经,自主神经,心脏和心理检查,对这两个病例的POIS原因进行了调查。结果:广泛的调查没有发现这些患者症状的主要器质性原因。详细的病史揭示了每种情况下可能不同的病因。在一种情况下,症状图片提示细胞因子释放,实际上,患者在性高潮之前和之后一两天服用非甾体类抗炎药可主观上提高80%。另一例似乎具有与“ Dhat”综合征相关的种族/文化病因。结论:这些病例的病因/临床关联明显不同,突显了对患有POIS的患者进行仔细的病史,检查和检查的必要性。我们建议每个案例都需要进行个别考虑和调查,并且需要针对可能的原因调整治疗方案。 POIS可能代表了一系列不同病因的综合症。对性高潮的神经生化后遗症的进一步研究将有助于理解这些情况下的病理过程。

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