• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of sexual medicine >Functional cortical and subcortical abnormalities in pedophilia: a combined study using a choice reaction time task and fMRI.
【24h】

Functional cortical and subcortical abnormalities in pedophilia: a combined study using a choice reaction time task and fMRI.

机译：恋童癖中的功能性皮质和皮质下异常：一项使用选择反应时间任务和fMRI的联合研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

INTRODUCTION: Pedophiles show sexual interest in prepubescent children but not in adults. Research into the neurofunctional mechanisms of paraphilias has gathered momentum over the last years. AIM: To elucidate the underlying neural processing of sexual interest among pedophiles and to highlight the differences in comparison with nonparaphilic sexual interest in adults. METHODS: Nine pedophilic patients and 11 nonpedophilic control subjects underwent functional magnetic resonance imaging (fMRI) while viewing pictures of nude (prepubescents, pubescents, and adults) and neutral content, as well as performing a concomitant choice reaction time task (CRTT). MAIN OUTCOME MEASURES: Brain blood oxygen level-dependent (BOLD) signals and response latencies in the CRTT during exposure to each picture category. RESULTS: Analysis of behavioral data showed group differences in reaction times regarding prepubescent and adult but not pubescent stimuli. During stimulation with pictures displaying nude prepubescents, pedophiles showed increased BOLD response in brain areas known to be involved in processing of visual sexual stimuli. Comparison of pedophilic patients with the control group discovered differences in BOLD responses with respect to prepubescent and adult but not to pubescent stimuli. Differential effects in particular occurred in the cingulate gyrus and insular region. CONCLUSIONS: The brain response of pedophiles to visual sexual stimulation by images of nude prepubescents is comparable with previously described neural patterns of sexual processing in nonpedophilic human males evoked by visual stimuli depicting nude adults. Nevertheless, group differences found in the cingulate gyrus and the insular region suggest an important role of these brain areas in pedophilic sexual interest. Furthermore, combining attention-based methods like CRTT with fMRI may be a viable option for future diagnostic procedures regarding pedophilia.
机译：简介：恋童癖者在青春期前的儿童中表现出性兴趣，而在成年人中则没有。在过去的几年中，对亲友性神经功能机制的研究势头迅猛。目的：阐明恋童癖者对性兴趣的潜在神经处理，并强调与成人非亲性性兴趣相比的差异。方法：9名恋童癖患者和11名非恋童癖对照对象进行了功能磁共振成像（fMRI），同时查看裸照（青春期前，青春期和成年人）和中性含量的图像，并执行了伴随选择反应时间任务（CRTT）。主要观察指标：在暴露于每种图像类别期间，CRTT中脑血氧水平相关（BOLD）信号和响应潜伏期。结果：行为数据分析显示，关于青春期前和成人的反应时间存在群体差异，但没有青春期刺激的差异。在用裸露的青春期前图片进行刺激的过程中，恋童癖者在已知参与视觉性刺激处理的大脑区域显示出BOLD反应增强。恋童癖患者与对照组的比较发现，对于青春期前和成年人，但对于青春期刺激，BOLD反应差异。差异作用尤其发生在扣带回和岛状区域。结论：恋童癖者对裸体前青春期的图像进行视觉性刺激的大脑反应与先前描述的描绘裸体成年人的视觉刺激引起的非恋童性人类男性性加工的神经模式相当。尽管如此，在扣带回和岛状区域发现的群体差异表明，这些大脑区域在恋童癖性兴趣中具有重要作用。此外，将基于注意力的方法（如CRTT）与功能磁共振成像相结合可能是未来有关恋童癖诊断程序的可行选择。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号