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Physiology of Women's Sexual Function: Basic Knowledge and New Findings

机译:妇女性功能生理学:基础知识和新发现

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Introduction. Data concerning the physiology of female sexual functioning are still obtained from animal studies, but an increasing amount of novel evidence comes from human studies. Aim. To gain knowledge of psychological and biologic physiology of women's sexual functioning, mainly addressing sexual arousal and orgasm. Methods. A broad-based literature review of current knowledge of the psychological and biologic physiology aspects of women's sexual functioning. Results. A comprehensive understanding of the anatomical, neurobiological, and psychological mechanisms behind sexual function and responses is of paramount importance. A biopsychological paradigm was considered when reviewing currently available data, thus considering aspects of: (i) sexual differentiation of the brain, which is critical for sex differentiation in behavior; (ii) central neurobiology of sexual function, highlighting specific and innovative findings from neuroimaging methods that enable visualization of active brain areas during arousal and orgasm; and (iii) peripheral functional anatomy, mainly addressing genital arousal and orgasm. Translational science was also covered, providing data about the actual role of sexual arousal in women in both procreation/reproduction and recreation/pleasure. The interaction between physiological and psychological states of women's sexual response, nonspecific sexual response, interoceptive awareness, and flexibility of sexual interests have also been addressed. Conclusion. Further research on normal physiology of women's sexual function is needed in order to expand and "translate" current knowledge into the pathophysiological clinical setting. This manuscript encompasses data presented at the 3rd International Consultation on Sexual Medicine in Paris, France, July 10-13, 2009.
机译:介绍。仍从动物研究中获得有关女性性功能生理的数据,但越来越多的新证据来自人体研究。目标。获得女性性功能的心理和生物生理知识,主要解决性唤起和性高潮。方法。关于女性性功能的心理和生理生理方面的最新知识的广泛文献综述。结果。对性功能和反应背后的解剖,神经生物学和心理机制的全面理解至关重要。在审查当前可用数据时,考虑了一种生物心理学范式,因此考虑了以下方面:(i)大脑的性别分化,这对于行为中的性别分化至关重要; (ii)性功能的中枢神经生物学,强调了神经影像学方法的特定和创新发现,这些方法可以使唤醒和性高潮时活动的大脑区域可视化; (iii)外围功能解剖,主要针对生殖器唤醒和性高潮。还涵盖了转化科学,提供了有关性唤起在女性生殖/生殖和娱乐/愉悦中的实际作用的数据。还探讨了妇女性反应的生理和心理状态,非特异性性反应,感受性意识以及性兴趣灵活性之间的相互作用。结论。为了将现有知识扩展和“转化”到病理生理学临床环境中,需要进一步研究女性性功能的正常生理学。该手稿包含在2009年7月10日至13日在法国巴黎举行的第三届性医学国际磋商会上提供的数据。

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