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Vaginal Carcinoma in a Female-to-Male Transsexual

机译:女性对男性变性者的阴道癌

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Introduction. Sex reassignment surgery (SRS) can be considered a reasonable and secure treatment for transsexualism, today. Because the population of patients who have received SRS is growing steadily, it can be expected that the number of patients who present with diseases specific to their original gender will increase as well. Aim. In female-to-male transsexuals, vaginal cancer has not been reported so far. This article reports, to our knowledge, the first case of a female-to-male transsexual who developed vaginal cancer. Methods. Eighteen years after receiving female-to-male SRS, the patient presented with vaginal cancer, which infiltrated rectum and bladder and also showed involvement of inguinal lymph nodes. Surgery consisted of an anterior and posterior pelvic demolition and extended lymphadenectomy with preservation of the penoid and reconstruction of the pelvic defect with multiple flaps. Results. The tumor was removed completely (RO), and 2 years after surgery, the patient has no signs or symptoms of tumor recurrence and enjoys good quality of life. Conclusions. In SRS patients, diseases of their original gender should always be considered and patients should be encouraged to participate in screening programs. When choosing the surgical approach for SRS, the risks for developing cancer from remaining structures of the genetic gender should be considered. Of course, removal of e.g., ovaries, cervix and vagina, will prevent cancer of these structures. When it comes to surgery in SRS patients with malignancies, an interdisciplinary approach should be chosen.
机译:介绍。如今,性重分配手术(SRS)可以被认为是变性欲症的一种合理,安全的治疗方法。由于已接受SRS的患者人数在稳定增长,因此可以预见患有特定于其原始性别的疾病的患者数量也会增加。目标。迄今为止,在女性对男性的变性者中,没有阴道癌的报道。据我们所知,这篇文章报道了第一例发生阴道癌的男女变性人。方法。接受雌雄SRS十八年后,患者出现阴道癌,浸润直肠和膀胱,还表现出腹股沟淋巴结受累。手术包括骨盆的前,后拆除和扩大的淋巴结清扫术,保留了股骨,并通过多个皮瓣重建了骨盆缺损。结果。肿瘤已完全切除(RO),并且手术后2年,患者没有肿瘤复发的迹象或症状,并享有良好的生活质量。结论。在SRS患者中,应始终考虑其原始性别的疾病,并应鼓励患者参加筛查计划。在选择SRS的手术方法时,应考虑到遗传性别的其余结构发展为癌症的风险。当然,去除例如卵巢,子宫颈和阴道将防止这些结构的癌症。当涉及SRS恶性肿瘤患者的手术时,应选择跨学科方法。

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