• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of sexual medicine >Interstitial cystitis is associated with vulvodynia and sexual dysfunction--a case-control study.
【24h】

Interstitial cystitis is associated with vulvodynia and sexual dysfunction--a case-control study.

机译：间质性膀胱炎与外阴痛和性功能障碍有关-病例对照研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

INTRODUCTION: Dyspareunia and sexual dysfunction are common in women with urological disorders. The study of comorbidity between interstitial cystitis (IC) and vulvodynia seems to be relevant to understand the mechanism generating pain in these conditions. AIM: To conduct a case-control study for evaluating vulvodynia and sexual dysfunction in women with IC. METHODS: Forty-seven women with new diagnosis (National Institutes of Health [NIH]/National Institute of Diabetes and Digestive and Kidney Diseases [NIDDK] Criteria) of IC were compared with 188 age-matched, negative controls. Each woman completed a semi-structured interview and the Female Sexual Function Index (FSFI). A gynecological examination to assess vulvodynia (cotton swab testing) and genital health (vulvoscopy, Pap smear, culture, and vaginal health index score [VHIS]) was performed. MAIN OUTCOME MEASURES: Prevalence of vulvodynia, sexual function, and sociodemographic/gynecological variables significantly associated with IC. RESULTS: Spontaneous or provoked vulvodynia was reported by 23.4% and 74.5% of IC cases, respectively. Sexual function was significantly impaired (median total FSFI score: IC cases 16.85 +/- 8.73 vs. controls 27.34 +/- 6.41; P<0.0001) in sexually active women, and 23.4% of IC cases as compared to 9% of controls reported no sexual activity in the year preceding the study (chi(2) for trend=38.2, P<0.0001). VHIS was highly impaired in women with IC in comparison with controls (P<0.0001). Variables significantly associated with IC were a diagnosis of menopause (odds ratio [OR]=31.2, 95% confidence interval [CI]=8.1-120.5), past (OR=4.6, 95% CI=1.74-12.1) or current (OR=6.9, 95% CI=2.1-22.1) oral contraceptive use, and a histologically confirmed diagnosis of endometriosis (OR=3.7, 95% CI=1.1-12.7). CONCLUSION: We found an increased prevalence of vulvodynia among women with recently diagnosed IC; both conditions seem to have profound consequences on women's sexual function. A potential role for sex hormone-dependent mechanisms into the comorbidity of vulvar and bladder pain is proposed, but further research is warranted.
机译：引言：泌尿系统疾病女性易发生性交困难和性功能障碍。间质性膀胱炎（IC）和外阴痛合并症的研究似乎与了解在这些情况下产生疼痛的机制有关。目的：进行一项病例对照研究，以评估IC女性的外阴痛和性功能障碍。方法：将四十七名新诊断为IC的妇女（美国国立卫生研究院[NIH] /美国糖尿病与消化与肾脏疾病研究所[NIDDK]标准）与188名年龄匹配的阴性对照进行比较。每个妇女都完成了半结构化访谈和女性性功能指数（FSFI）。进行妇科检查以评估外阴痛（棉签测试）和生殖器健康（外阴镜检查，子宫颈抹片检查，培养和阴道健康指数评分[VHIS]）。主要观察指标：外阴痛，性功能和社会人口统计学/妇科变量的患病率与IC显着相关。结果：自发性或诱发性外阴痛分别占IC病例的23.4％和74.5％。性活跃女性的性功能显着受损（中位FSFI总评分：IC病例为16.85 +/- 8.73，对照组为27.34 +/- 6.41; P <0.0001），IC病例为23.4％，而对照组为9％在研究之前的一年中没有性活动（趋势为38.2的chi（2），P <0.0001）。与对照组相比，有IC的女性VHIS严重受损（P <0.0001）。与IC显着相关的变量是更年期的诊断（赔率[OR] = 31.2，95％置信区间[CI] = 8.1-120.5），过往（OR = 4.6、95％CI = 1.74-12.1）或当前（OR = 6.9，95％CI = 2.1-22.1）口服避孕药，并在组织学上确诊为子宫内膜异位症（OR = 3.7，95％CI = 1.1-12.7）。结论：我们发现最近被诊断为IC的女性的外阴痛患病率增加。两种情况似乎都对女性的性功能产生深远影响。有人提出性激素依赖机制在外阴和膀胱疼痛合并症中的潜在作用，但有待进一步研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号