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首页> 外文期刊>The journal of sexual medicine >Sexual functioning in male survivors of lymphoma: a systematic review (CME).
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Sexual functioning in male survivors of lymphoma: a systematic review (CME).

机译：男性淋巴瘤幸存者的性功能：系统评价（CME）。

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INTRODUCTION: The lymphomas (Hodgkin's lymphoma [HL] and non-Hodgkin's lymphoma [NHL]) are among the most common cancers affecting men under 45 years. Survival rates are now excellent, but treatment is associated with a number of side effects including sexual dysfunction with potential implications for compromised quality of life (QoL). AIMS: To address the (i) prevalence of sexual dysfunction among lymphoma survivors relative to the general population, survivors of other cancers, and in survivors of HL and NHL; and (ii) relationships between sexual functioning and disease and treatment, demographic, and psychological variables. METHODS: Inclusion criteria were quantitative studies that focused on adult male survivors of lymphoma and included a comparison group and presented results separately for HL and NHL. Standardized systematic searches were used. Information about design, sample size, age, time since diagnosis, type of treatment, comparison group, measures, and findings were extracted from eligible studies. RESULTS: Ten articles met the inclusion criteria, of which, nine included patients with HL only, and one included patients with HL or NHL. Sexual function was compromised relative to the general population, better than testicular cancer survivors, and worse than leukemia survivors. Depression was consistently associated with sexual dysfunction. There was evidence that chemotherapy, relapse, reduced testosterone levels, older age at survey, and worse physical QoL were associated with worse sexual function. CONCLUSIONS: Conclusions are limited by methodological issues including lack of utilization of standardized measures of sexual function and longitudinal research. Even so, there is evidence of sexual dysfunction among lymphoma survivors. Clinicians need to be sensitive to these issues. Future longitudinal work is necessary to determine the likelihood of recovery.
机译：简介：淋巴瘤（霍奇金淋巴瘤[HL]和非霍奇金淋巴瘤[NHL]）是影响45岁以下男性的最常见癌症。现在，存活率非常好，但治疗会带来许多副作用，包括性功能障碍，可能会影响生活质量（QoL）。目的：（i）相对于普通人群，其他癌症的幸存者以及HL和NHL的幸存者，淋巴瘤幸存者中性功能障碍的患病率; （ii）性功能与疾病，治疗，人口和心理变量之间的关系。方法：纳入标准是针对成年男性淋巴瘤幸存者的定量研究，包括一个对照组，并分别报告了HL和NHL的结果。使用标准化的系统搜索。有关设计，样本量，年龄，诊断以来的时间，治疗类型，对照组，措施和发现的信息均来自符合条件的研究。结果：10篇符合入选标准的文章，其中9篇仅包括HL患者，另一篇包括HL或NHL患者。相对于一般人群，性功能受到损害，比睾丸癌幸存者好，比白血病幸存者差。抑郁症一直与性功能障碍有关。有证据表明，化疗，复发，睾丸激素水平降低，调查时的年龄变大以及身体质量的恶化与性功能下降有关。结论：结论受到方法学问题的限制，包括缺乏对性功能的标准化测量和纵向研究的利用。即便如此，仍有证据表明淋巴瘤幸存者中存在性功能障碍。临床医生需要对这些问题保持敏感。未来的纵向工作对于确定恢复的可能性是必要的。

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