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Depression resulting from olfactory dysfunction is associated with reduced sexual appetite--a cross-sectional cohort study.

机译:一项嗅觉功能障碍导致的抑郁与性欲降低有关-一项横断面队列研究。

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INTRODUCTION: Anecdotal reports from patients with smell loss provided the basic motivation for the present study on sexual dysfunction among patients with olfactory dysfunction. The aim of the present study was to investigate the sexual appetite and the subject's depression in regard to olfactory function. METHODS: Eighty-six patients referred to our smell and taste clinic with olfactory dysfunction were investigated. Olfactory function was assessed by means of the Sniffin' Sticks discrimination (D), and odor identification (I). Their results were summed up to a composite score, the so-called "TDI score." All participants completed a questionnaire including the Beck Depression Inventory (BDI) and 11 questions for evaluation of the sexual appetite in regard to the time before the onset of olfactory dysfunction and since the olfactory dysfunction. The points received for the latter questions were summed up to the so called Sexual Appetite Index (SAI). RESULTS: Olfactory testing revealed that 38 patients were functionally anosmic, 39 patients were hyposmic, and nine patients were normosmic. The average BDI score was 11.0 +/- 8.4 points. Evaluation of the SAI questionnaire revealed a significant decrease (P = 0.003) of the score from 22.7 +/- 4.5 points from the time before to 21.4 +/- 4.9 points since the onset of olfactory loss. No significant correlation was found between olfactory function and the SAI since the onset of olfactory dysfunction. However, the BDI score correlated negatively with the SAI since the onset of olfactory dysfunction (r(85) = -0.36; P = 0.001). CONCLUSION: The present study does not confirm the hypothesis that loss of olfactory function directly impacts on sexual appetite. It seems that depression caused by olfactory loss is the main cause for the self-reported decrease in sexual appetite as the onset of olfactory dysfunction.
机译:简介:嗅觉丧失患者的轶事报道为本研究中嗅觉功能障碍患者的性功能障碍提供了基本动机。本研究的目的是调查关于嗅觉功能的性欲和受试者的抑郁。方法:对转诊至我们的嗅觉和味觉诊所嗅觉功能障碍的86例患者进行了调查。通过嗅探棒辨别力(D)和气味识别(I)评估嗅觉功能。他们的结果被汇总为一个综合评分,即所谓的“ TDI评分”。所有参与者均完成了问卷调查,包括贝克抑郁量表(BDI)和11个问题,以评估与嗅觉障碍发作之前和嗅觉障碍以来的时间有关的性欲。后一个问题获得的分数被汇总为所谓的性欲指数(SAI)。结果:嗅觉测试显示38例功能性厌氧症患者,39例低渗性患者,9例正常性患者。 BDI的平均得分为11.0 +/- 8.4分。对SAI问卷的评估显示,自嗅觉丧失以来,评分从之前的22.7 +/- 4.5分显着降低(P = 0.003)至21.4 +/- 4.9分。自嗅觉功能障碍发作以来,在嗅觉功能和SAI之间未发现显着相关性。但是,自嗅觉功能障碍发作以来,BDI评分与SAI呈负相关(r(85)= -0.36; P = 0.001)。结论:本研究并未证实嗅觉丧失直接影响性欲的假说。由于嗅觉功能障碍的发作,似乎是由嗅觉丧失引起的抑郁症是自我报告的性欲下降的主要原因。

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