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Please note the following correction to the abstract of the above referenced paper. Introduction. There is no current consensus as to the most effective non-surgical therapy for Peyronie's disease (PD). Aim. To assess the benefit of penile traction therapy (PTT) when added to intralesional verapamil injections (TVI) combined with oral L-arginine lg bid and pentoxifylline 400 mg tid in men with PD.Methods. 74 men with PD completed 12 IVI. Patients electing to add PTT were advised to wear the device for 2-8 hours daily, and no longer than 2 hours per session. Subjective responses were measured using patient questionnaires. Stretched penile length (SPL) and erect penile curvature (EPC) using penile duplex ultrasound (DU) were measured. Response to therapy was defined as at least a 10 degree reduction in EPC.Main Outcome Measures. Change in SPL (cm), change in EPC (degrees).Results. 39 patients in the PTT group (I) vs. 35 patients in group (II) completed the protocol. 54% of men in group I responded to therapy vs. 46% in group II (p = 0.75). Responders had a mean EPC improvement of 26.9 degrees in group I vs. 20.9 in group II (p = 0.22). Mean PTT use was 3.3 hours per day, and men with >3 hours per day use gained 0.6 cm in SPL vs 0.07 cm using less than or equal to 3 hours per day (p = 0.09), while men in group I on lost 0.74 cm of SPL on average. Multivariate analysis revealed that duration of PTT use significantly predicts length gain (0.38 cm gain for every additional hour per day of PTT use, p = 0.007).Conclusion. There was a trend toward measured curvature improvement, and a significant gain in SPL in men using the combination therapy protocol. Length improvement is related to duration of use of the traction device.
机译:请注意以下对上述参考文件摘要的更正。介绍。对于佩罗尼氏病(PD)的最有效的非手术疗法,目前尚无共识。目标。为了评估将PD男性患者的病灶内维拉帕米注射液(TVI)与口服L-精氨酸lg bid和己酮可可碱400 mg tid联合使用时的阴茎牵引疗法(PTT)的益处。 74名PD病患完成了12 IVI。建议选择添加PTT的患者每天佩戴该设备2-8小时,每次疗程不超过2小时。使用患者问卷测量主观反应。使用阴茎双工超声(DU)测量了伸长的阴茎长度(SPL)和勃起的阴茎曲率(EPC)。对治疗的反应定义为EPC至少降低10度。主要指标。 SPL(厘米)变化,EPC(度)变化。结果。 PTT组(I)中的39名患者与组(II)中的35名患者完成了方案。第一组的男性对治疗有反应,而第二组的男性为46%(p = 0.75)。与第一组相比,第一组应答者的平均EPC改善了26.9度(P = 0.22)。平均每天使用PTT的时间为3.3小时,每天使用时间大于3小时的男人在SPL中的身高增加了0.6厘米,而每天少于或等于3个小时的人则增加了0.07厘米(p = 0.09),而第一组的男人则减少了0.74平均SPL厘米。多变量分析显示,使用PTT的持续时间显着预测了长度增加(每天使用PTT的每一小时增加0.38厘米,p = 0.007)。结论。使用联合治疗方案的男性有明显的曲率改善趋势,并且SPL显着增加。长度的增加与牵引装置的使用时间有关。

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