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首页> 外文期刊>The journal of sexual medicine >Vascular risk factors as predictors of sexual function following coronary artery bypass graft.
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Vascular risk factors as predictors of sexual function following coronary artery bypass graft.

机译：血管危险因素可作为冠状动脉旁路移植术后性功能的预测指标。

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INTRODUCTION: A strong association between cardiovascular risk factors and erectile dysfunction (ED) was suggested. Coronary artery bypass grafting (CABG) is the gold standard for surgical myocardial revascularization. AIM: We herein evaluate the impact of vascular risk factors on postoperative sexual functions in patients undergo CABG. MAIN OUTCOME MEASURES: ED severity by the International Index of Erectile Function (IIEF-5) and penile duplex study. METHODS: The present study included 100 patients who underwent CABG. The patients were evaluated by an abridged form of the IIEF-5 questionnaire, followed by CABG. Six months after surgery the erectile function of all patients was re-evaluated utilizing the IIEF-5. RESULTS: Number of risk factors was significantly associated with postoperative change in IIEF-5 score (P = 0.02). A post hoc analysis of the association revealed that patients with one risk factor were significantly more likely to have increased IIEF-5 scores (N = 18), whereas those with two or more risk factors were significantly more likely to have decreased IIEF-5 scores (N = 21, P < 0.05). Furthermore, those with no risk factors were significantly more likely to be stable (N = 8) compared with those with more than two risk factors, who were more likely to have decreased scores (P < 0.05). The hierarchical logistic regression results showed that when examining all risk factors simultaneously, because of multicollinearity, only hyperlipidemia was significantly associated with postoperative ED (odds ratio [OR] = 11.33, confidence interval [CI] = 1.25, 102.82). Frequency of intercourse was also significantly associated with postoperative ED after controlling for risk factors (OR = 0.71, CI = 0.52, 0.97). CONCLUSIONS: This data clearly shows that the number of cardiovascular risk factors is an essential predictive factor for sexual function following surgery. Only hyperlipidemia may play a predictive role for the future sexual function of patients undergo CABG.
机译：简介：心血管疾病危险因素与勃起功能障碍（ED）之间存在强烈的关联。冠状动脉旁路移植术（CABG）是外科手术心肌血运重建的金标准。目的：我们在此评估接受CABG的患者中血管危险因素对术后性功能的影响。主要观察指标：根据国际勃起功能指数（IIEF-5）和阴茎双工研究对ED的严重程度进行评估。方法：本研究包括100例行CABG的患者。通过简短形式的IIEF-5问卷评估患者，然后进行CABG评估。手术六个月后，使用IIEF-5重新评估了所有患者的勃起功能。结果：危险因素的数量与IIEF-5评分的术后变化显着相关（P = 0.02）。对该关联的事后分析显示，具有一个危险因素的患者IIEF-5评分升高的可能性更高（N = 18），而具有两个或更多危险因素的患者IIEF-5评分降低的可能性更高（N = 21，P <0.05）。此外，与那些具有两个以上危险因素的人相比，那些没有危险因素的人稳定的可能性明显更高（N = 8），而他们的得分降低的可能性更大（P <0.05）。分层逻辑回归结果显示，当同时检查所有危险因素时，由于多重共线性，只有高脂血症与术后ED显着相关（比值比[OR] = 11.33，置信区间[CI] = 1.25，102.82）。控制危险因素后，性交频率也与术后ED密切相关（OR = 0.71，CI = 0.52，0.97）。结论：该数据清楚地表明，心血管危险因素的数目是手术后性功能的重要预测因素。只有高脂血症才能对接受CABG的患者未来的性功能起到预测作用。

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