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首页> 外文期刊>The journal of sexual medicine >Changes in sexual functioning in women after neuromodulation for voiding dysfunction
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Changes in sexual functioning in women after neuromodulation for voiding dysfunction

机译：排尿障碍的神经调节后女性性功能的变化

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Introduction: Sacral neuromodulation is a well-established treatment for urinary and bowel disorders with potential use for other disorders such as sexual dysfunction. Aim: To evaluate changes in sexual functioning in women undergoing neuromodulation for voiding symptoms. Methods: Patients enrolled in our prospective, observational neuromodulation database study were evaluated. Data were collected from medical records, and patient-completed Female Sexual Function Index (FSFI) and Interstitial Cystitis Symptom-Problem Indices (ICSI-PI) at baseline, 3, 6, and 12 months post-implant. Patients rated overall change in sexual functioning on scaled global response assessments (GRA) at 3, 6, and 12 months post-implant. We grouped women by baseline FSFI scores: less (score<26) and more sexually functional (score≥26). Data were analyzed with Pearson's Chi-square or Fisher's Exact test and repeated measures. Main Outcomes Measures: Changes in FSFI and ICSI-PI scores in women grouped by baseline FSFI score<26 and ≥26. Results: Of 167 women evaluated, FSFI scores improved overall from preimplant (mean 13.5±8.5) to 12 months (N=72; mean 15.9±8.9, P=0.004). At baseline and each follow-up point, ICSI-PI scores were similar between groups and improved through time. For patients in the FSFI<26 group there was improvement from baseline to 12-month scores (N=63; 11.9±6.9 to 14.8±8.7; P=0.0006). Improved FSFI domains included desire, orgasm, satisfaction, and pain. Furthermore, of the 74 subjects in this group not sexually active at baseline, 10 became sexually active during follow-up. In the FSFI≥26 group there was slight but statistically significant decline in mean scores between baseline and 12 months (N=9; 27.4±1.1 to 24.5±3.4; P=0.0302); however one had become sexually inactive. A significant decrease was seen in the satisfaction domain. Conclusions: Many factors affect sexual functioning in women; however sexual function may improve along with urinary symptoms after neuromodulation.
机译：简介：neuro神经调节是一种公认​​的治疗泌尿和肠道疾病的方法，可用于其他疾病，例如性功能障碍。目的：评估因排尿症状而进行神经调节的女性的性功能变化。方法：对参与我们的前瞻性，观察性神经调节数据库研究的患者进行了评估。从医疗记录中收集数据，在植入后，植入后3、6和12个月，患者完成的女性性功能指数（FSFI）和间质性膀胱炎症状问题指数（ICSI-PI）。患者在植入后3个月，6个月和12个月时，通过规模化整体反应评估（GRA）对性功能的总体变化进行了评估。我们按照基线FSFI分数对女性进行了分组：更少（得分<26）和性功能更高（得分≥26）。数据通过Pearson卡方检验或Fisher精确检验和重复测量进行分析。主要结局指标：按基线FSFI得分<26和≥26分组的女性FSFI和ICSI-PI得分的变化。结果：在167名接受评估的女性中，FSFI评分从植入前（平均13.5±8.5）到12个月总体改善（N = 72;平均15.9±8.9，P = 0.004）。在基线和每个随访点，两组间的ICSI-PI得分相似，并且随着时间的推移而提高。对于FSFI <26组的患者，从基线到12个月评分都有改善（N = 63; 11.9±6.9至14.8±8.7; P = 0.0006）。改进的FSFI域包括欲望，性高潮，满意度和痛苦。此外，该组中的74名受试者在基线时没有性活跃，其中10名在随访期间变得有性活跃。在FSFI≥26组中，基线和12个月之间的平均得分有轻微但统计学上的显着下降（N = 9; 27.4±1.1至24.5±3.4; P = 0.0302）;但是，其中一个人变得性不活跃。在满意度方面，看到了显着的下降。结论：许多因素影响女性的性功能。然而，在进行神经调节后，性功能会随着泌尿症状而改善。

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