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首页> 外文期刊>The journal of sexual medicine >Effects of Different Steps in Gender Reassignment Therapy on Psychopathology: A Prospective Study of Persons with a Gender Identity Disorder
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Effects of Different Steps in Gender Reassignment Therapy on Psychopathology: A Prospective Study of Persons with a Gender Identity Disorder

机译：性别再分配治疗中不同步骤对心理病理学的影响：性别认同障碍者的前瞻性研究

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Introduction: At the start of gender reassignment therapy, persons with a gender identity disorder (GID) may deal with various forms of psychopathology. Until now, a limited number of publications focus on the effect of the different phases of treatment on this comorbidity and other psychosocial factors. Aims: The aim of this study was to investigate how gender reassignment therapy affects psychopathology and other psychosocial factors. Methods: This is a prospective study that assessed 57 individuals with GID by using the Symptom Checklist-90 (SCL-90) at three different points of time: at presentation, after the start of hormonal treatment, and after sex reassignment surgery (SRS). Questionnaires on psychosocial variables were used to evaluate the evolution between the presentation and the postoperative period. The data were statistically analyzed by using SPSS 19.0, with significance levels set at P<0.05. Main Outcome Measures: The psychopathological parameters include overall psychoneurotic distress, anxiety, agoraphobia, depression, somatization, paranoid ideation/psychoticism, interpersonal sensitivity, hostility, and sleeping problems. The psychosocial parameters consist of relationship, living situation, employment, sexual contacts, social contacts, substance abuse, and suicide attempt. Results: A difference in SCL-90 overall psychoneurotic distress was observed at the different points of assessments (P=0.003), with the most prominent decrease occurring after the initiation of hormone therapy (P<0.001). Significant decreases were found in the subscales such as anxiety, depression, interpersonal sensitivity, and hostility. Furthermore, the SCL-90 scores resembled those of a general population after hormone therapy was initiated. Analysis of the psychosocial variables showed no significant differences between pre- and postoperative assessments. Conclusions: A marked reduction in psychopathology occurs during the process of sex reassignment therapy, especially after the initiation of hormone therapy.
机译：简介：在开始进行性别重新分配治疗时，患有性别认同障碍（GID）的人可能会处理各种形式的心理病理学。到目前为止，只有少数出版物关注治疗的不同阶段对该合并症和其他社会心理因素的影响。目的：本研究的目的是调查性别重新分配疗法如何影响心理病理学和其他社会心理因素。方法：这是一项前瞻性研究，通过在三个不同的时间点使用症状检查清单-90（SCL-90）评估了57名GID个体：在就诊时，激素治疗开始后以及性交手术后（SRS） 。关于社会心理变量的问卷被用来评估从表现到术后时期的演变。使用SPSS 19.0统计分析数据，显着性水平设置为P <0.05。主要观察指标：心理病理学参数包括整体精神神经疾病困扰，焦虑，恐惧心理，抑郁症，躯体化，偏执观念/精神病，人际关系敏感，敌意和睡眠问题。社会心理参数包括关系，生活状况，就业，性接触，社会接触，药物滥用和自杀企图。结果：在评估的不同点观察到SCL-90总体精神神经病困扰的差异（P = 0.003），最显着的下降发生在激素治疗开始后（P <0.001）。在诸如焦虑，抑郁，人际关系敏感和敌对等分量表中发现了明显的下降。此外，激素治疗开始后，SCL-90评分与一般人群相似。对社会心理变量的分析显示，术前和术后评估之间无显着差异。结论：在性别重新分配治疗的过程中，尤其是在开始激素治疗后，精神病理学显着减少。

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