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首页> 外文期刊>The journal of sexual medicine >Vasculogenic erectile dysfunction is a predictor of abnormal stress echocardiography.
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Vasculogenic erectile dysfunction is a predictor of abnormal stress echocardiography.

机译：血管源性勃起功能障碍是应激性超声心动图异常的预测指标。

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INTRODUCTION: Erectile dysfunction (ED) and atherosclerotic vascular disease have the same risk factors; furthermore, endothelial dysfunction has been shown to be a common link between these conditions. A high prevalence of silent coronary artery disease (CAD) in patients with ED has been observed. AIMS: The aims of this article were to define the prevalence and identify predictors of occult obstructive CAD in patients with documented vasculogenic ED. MAIN OUTCOME MEASURES: Duplex Doppler penile ultrasonography (DUS); exercise stress echocardiography; IIEF; CAD risk factors. Methods. Patients presenting with ED who had penile vascular insufficiency documented by DUS and who had no history of diabetes or symptoms of CAD were prospectively enrolled for noninvasive cardiac stress testing using exercise stress echocardiography. RESULTS: Forty-nine men (mean age 517 years) with an average duration of ED of 2.52 years were evaluated. Penile arterial insufficiency was present in 94%, and venous leak in 20% of patients. Comorbidities included hypertension (51%), hyperlipidemia (41%), and smoking (35%). All patients had at least one vascular risk factor, with 40% having two, 15% three, and 15% four risk factors. Ten patients (20%) had abnormal cardiac stress test. On univariate analysis, age, IIEF-EF domain score, cavernosal artery insufficiency, presence of venous leak, and history of a first-degree relative with CAD were significant predictors. On multivariate analysis, cavernosal artery insufficiency, venous leak, and family history of CAD continued to be predictors of an abnormal stress test. CONCLUSIONS: A significant proportion of men with vasculogenic ED have abnormal cardiac stress test. The greatest chance for abnormal cardiac stress test was observed in those with corporo-venocclusive dysfunction or family history of CAD. In some men presenting with ED, even without a CAD history, performing penile DUS or cardiology referral for stress testing should be considered.
机译：简介：勃起功能障碍（ED）和动脉粥样硬化性血管疾病具有相同的危险因素。此外，已经证明内皮功能障碍是这些病症之间的常见联系。 ED患者中无症状冠状动脉疾病（CAD）的患病率很高。目的：本文的目的是确定有血管生成性ED的患者的隐匿性CAD的患病率并确定其预测因素。主要观察指标：双工多普勒阴茎超声检查（DUS）;运动压力超声心动图; IIEF; CAD风险因素。方法。 DUS记录的具有ED的阴茎血管功能不全且无糖尿病史或CAD症状的ED患者前瞻性纳入使用运动压力超声心动图的无创性心脏压力测试。结果：对平均ED持续时间为2。52年的49名男性（平均年龄517岁）进行了评估。阴茎动脉功能不全的比例为94％，静脉渗漏的比例为20％。合并症包括高血压（51％），高脂血症（41％）和吸烟（35％）。所有患者均具有至少一种血管危险因素，其中40％具有两个，15％三种和15％四种危险因素。十名患者（20％）的心脏压力测试异常。在单因素分析中，年龄，IIEF-EF域评分，海绵体动脉供血不足，静脉渗漏的存在以及与CAD的一级亲属史是重要的预测指标。在多变量分析中，海绵体动脉供血不足，静脉渗漏和CAD家族史继续是异常压力测试的预测因素。结论：相当一部分患有血管生成性ED的男性心脏压力测试异常。患有心脏-静脉闭塞功能障碍或有CAD家族史的人，发生异常心脏压力测试的机会最大。在一些患有ED的男性中，即使没有CAD史，也应考虑进行阴茎DUS或心脏内科转诊以进行压力测试。

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