Preserved Erectile Function in the Aged Transgenic Rat Harboring Human Tissue Kallikrein 1

Luan Yang; Ruan Yajun; Wang Tao; Zhuan Li; Wen Zheng; Chen Ruibao; Zhang Yan; Cui Kai; Yang Jun; Wang Shaogang; Liu Jihong; Ye Zhangqun; Wang Daowen

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Preserved Erectile Function in the Aged Transgenic Rat Harboring Human Tissue Kallikrein 1

机译：在怀有人类组织激肽释放酶1的转基因大鼠中保存勃起功能。

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Introduction: Human tissue kallikrein 1 (hKLK1) has enormous potential for the protection of vasodilation and endothelial function in the cardiovascular system. Our previous study proved the decreased expression of kallikrein 1 in the corpus cavernosum (CC) of aged rats, but the role of kallikrein 1 in age-related erectile dysfunction remains unknown.

机译：简介：人组织激肽释放酶1（hKLK1）在心血管系统中具有保护血管舒张和内皮功能的巨大潜力。我们之前的研究证明了激肽释放酶1在老年大鼠海绵体（CC）中的表达降低，但激肽释放酶1在与年龄相关的勃起功能障碍中的作用仍然未知。

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来源
《The journal of sexual medicine》 |2016年第9期|共12页
作者
Luan Yang; Ruan Yajun; Wang Tao; Zhuan Li; Wen Zheng; Chen Ruibao; Zhang Yan; Cui Kai; Yang Jun; Wang Shaogang; Liu Jihong; Ye Zhangqun; Wang Daowen;
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正文语种 eng
中图分类性卫生;
关键词
Erectile Dysfunction; Kallikrein 1; Aged; Cyclic Guanosine Monophosphate; Fibrosis; Gene Therapy;

机译：勃起功能障碍;激肽释放酶1;衰老;单磷酸环鸟苷;纤维化;基因治疗;

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1. Preserved Erectile Function in the Aged Transgenic Rat Harboring Human Tissue Kallikrein 1 [J] . Luan Yang, Ruan Yajun, Wang Tao, The journal of sexual medicine . 2016,第9期

机译：在怀有人类组织激肽释放酶1的转基因大鼠中保存勃起功能。
2. PRESERVED ERECTILE FUNCTION IN THE HYPERHOMOCYSTEINAEMIA TRANSGENIC RATS HARBORING HUMAN TISSUE KALLIKREIN 1 [J] . Cui K., Tang Z., Luan Y., The journal of sexual medicine . 2018,第7Suppla3期

机译：保存的勃起功能在含人组织Kallikrein的Hyperhomysteina血症转基因大鼠1
3. Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1 [J] . Kai Cui, Yang Luan, Tao Wang, Asian journal of andrology . 2017,第1期

机译：通过抑制携带人组织激肽释放酶1的老年转基因大鼠的Rho激酶/ LIM激酶/ cofilin途径，减少体质纤维化以保护勃起功能
4. In Vivo Study of Adenovirus Mediated Transgenic HIF-1alpha and Its Protective Effects on Cardiac Function - Biochemical, Cellular, Molecular and Tissue Engineering [C] . Li Dong-Ye, Yan Yan, Zhu Hong, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

机译：腺病毒介导的转基因HIF-1alpha的体内研究及其对心脏功能的保护作用-生化，细胞，分子和组织工程
5. A structure-function analysis of the lysine-binding kringle 2 domains of human tissue-type plasminogen activator and human plasminogen by strategic mutagenesis. [D] . Nilsen, Stephanie Lynn. 1999

机译：通过战略诱变对人体组织型纤溶酶原激活物和纤溶酶原的赖氨酸结合kringle 2域的结构功能分析。
6. AB087. Preserved erectile function in the hyperhomocysteinaemia transgenic rats harboring human tissue kallikrein [O] . Kai Cui, Zhe Tang, Yang Luan, 2017

机译：AB087。携带人激肽释放酶的高同型半胱氨酸血症转基因大鼠的勃起功能得以维持
7. Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1 [O] . Kai Cui, Yang Luan, Tao Wang, 2017

机译：通过抑制携带人组织激肽释放酶1的老龄转基因大鼠中的Rho激酶/ LIm激酶/ cofilin途径来减少体内纤维化以保护勃起功能

Preserved Erectile Function in the Aged Transgenic Rat Harboring Human Tissue Kallikrein 1

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