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Persistent Sexual Dysfunction Impairs Quality of Life after Cardiac Transplantation

机译:持久性功能障碍会损害心脏移植后的生活质量

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Introduction. The impact of sexual dysfunction (SD) on mental and physical health after heart transplantation (HTx) has not been established. Aim. We investigated the relationship of SD on quality of life (QoL), physical and mental health, and depressive symptoms after HTx. Main Outcome Measures. We evaluated SD according to the International Index of Erectile Dysfunction and the Female Sexual Function Index. QoL, physical and mental health were assessed using: 1) Short Form 12 Health Survey Questionnaire, 2) Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form, and two depressive symptoms questionnaires: 1) Beck Depression Inventory-II and 2) Quick Inventory Depressive Symptomatology-Self Report. Methods. We enrolled patients who were greater than 6 months post HTx. Patients unable to read English, had pelvic surgery or trauma, urogenital abnormalities, or sexually inactive were excluded. Results. Out of 79 subjects that were screened, 33 men and 6 women participated (mean age 61.4 + 11.4). Response rates were at least 82% for all questionnaires. Overall prevalence of SD was 61%, with 78% of men being affected and 50% of women. There was no significant difference in measures between genders. HTx recipients with SD reported significantly worse QoL on measures of physical health when compared to those without SD. After HTx, patients suffering from SD had significantly worse general health (P = 0.02) and physical health (P = 0.02), including physical functioning (P = 0.01) and physical role limitation (P=0.01). In contrast, mental health and depressive symptoms after HTx were not significantly different between those with and without SD. Conclusions. After HTx a high prevalence of SD remains among both men and women. Patients with SD had worse general and physical health but not depressive symptoms when compared to those without SD. The contributing factors may be more related to physical rather than psychological causes.
机译:介绍。尚未确定性功能障碍(SD)对心脏移植(HTx)后心理和身体健康的影响。目标。我们调查了SD与HTx后生活质量(QoL),身心健康以及抑郁症状的关系。主要观察指标。我们根据国际勃起功能障碍指数和女性性功能指数对SD进行了评估。使用以下方法评估生活质量,身心健康:1)简短表格12健康调查问卷,2)生活质量和满意度问卷-简短表格,以及两个抑郁症状问卷:1)贝克抑郁量表II和2)快速量表抑郁症症状自我报告。方法。我们纳入了HTx后6个月以上的患者。无法阅读英语,进行过骨盆手术或外伤,泌尿生殖器异常或性不活跃的患者被排除在外。结果。在接受筛选的79位受试者中,有33位男性和6位女性参加了测试(平均年龄61.4 + 11.4)。所有问卷的回应率至少为82%。 SD的总体患病率为61%,其中78%的男性受到影响,而50%的女性受到影响。性别之间的措施没有显着差异。与没有SD的HTx接受者相比,有SD的HTx接受者在身体健康指标上的生活质量明显较差。 HTx后,患有SD的患者的总体健康状况(P = 0.02)和身体健康状况(P = 0.02)明显较差,包括身体机能(P = 0.01)和身体角色限制(P = 0.01)。相比之下,HTx后的精神健康和抑郁症状在有或没有SD者之间没有显着差异。结论。在HTx之后,无论男女,SD的患病率仍然很高。与没有SD的患者相比,SD的患者总体和身体健康较差,但没有抑郁症状。促成因素可能与生理原因而非心理原因更多相关。

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