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首页> 外文期刊>The Journal of toxicological sciences >Oral glucose tolerance test and determination of serum fructosamine level in beagle dogs.
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Oral glucose tolerance test and determination of serum fructosamine level in beagle dogs.

机译:比格犬的口服葡萄糖耐量试验和血清果糖胺水平的测定。

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摘要

The present communication deals with information regarding the practice of the oral glucose tolerance test and determination of serum fructosamine in laboratory beagles. In the oral glucose tolerance test, a 180-min level was found to be crucial following a gavage administration of 50% glucose solution at 5 mL/kg per body weight under fasting conditions. Serum fructosamine concentration as 'determined by enzymatic assay ranged between 82 and 123 micromol/L (mean of 104 micromol/L), which was about 0.285 to 0.25 times the value obtained by the chemical method described by Johnson and colleagues. Reasons for differences are ascribed to the presence of substances with reducing potential other than fructosamine in the serum.
机译:本来文涉及有关口服葡萄糖耐量试验的实践和实验室比格犬血清果糖胺测定的信息。在口服葡萄糖耐量试验中,在禁食条件下以每毫升5 mL / kg的剂量灌胃50%葡萄糖溶液后,发现180分钟的水平至关重要。通过酶法测定法测定的血清果糖胺浓度在82至123 micromol / L(平均104 micromol / L)之间,约为Johnson和同事描述的化学方法所得值的0.285至0.25倍。差异的原因归因于血清中果糖胺以外的物质具有降低电势的能力。

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