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首页> 外文期刊>The Journal of toxicological sciences >Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation.
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Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation.

机译:妊娠和哺乳期间暴露于镉的新生儿大脑的微阵列分析。

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摘要

DNA microarray containing 30,000 genes was used to monitor the transcriptional response of the neonatal brain after cadmium (Cd) exposure. C57BL/6J pregnant mice were exposed to Cd (10 ppm) during gestation and lactation via drinking water. In a comparison between the Cd-exposed neonatal brain and control, three genes including transferrin receptor (Tfrc) were up-regulated and one gene was down-regulated.
机译:包含30,000个基因的DNA微阵列用于监测镉(Cd)暴露后新生儿大脑的转录反应。 C57BL / 6J怀孕的小鼠在妊娠和哺乳期间通过饮用水暴露于Cd(10 ppm)。在Cd暴露的新生儿大脑与对照组之间的比较中,包括转铁蛋白受体(Tfrc)在内的三个基因被上调,而一个基因被下调。

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