Basophils and nephritis in lupus.

Kaveri SV; Mouthon L; Bayry J

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Basophils and nephritis in lupus.

机译：狼疮中的嗜碱性粒细胞和肾炎。

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Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease that predominantly affects the kidneys in the form of lupus nephritis, although multiple organs can be involved. Lupus nephritis is characterized by the deposition in glomeruli of immune complexes formed by IgG, IgM, and IgA autoantibodies (which collectively are called antinuclear antibodies). These autoantibodies are directed toward ubiquitous nuclear antigens, particularly double-stranded DNA.1 Deposition of these complexes can result in renal failure and even death.

机译：系统性红斑狼疮（SLE）是一种复杂的系统性自身免疫疾病，尽管可能涉及多个器官，但主要以狼疮性肾炎的形式影响肾脏。狼疮性肾炎的特征是由IgG，IgM和IgA自身抗体（统称为抗核抗体）形成的免疫复合物在肾小球中沉积。这些自身抗体针对普遍存在的核抗原，特别是双链DNA。1这些复合物的沉积可导致肾衰竭甚至死亡。

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《The New England journal of medicine》 |2010年第11期|共3页
作者
Kaveri SV; Mouthon L; Bayry J;
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正文语种 eng
中图分类医药、卫生;
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1. Basophils and nephritis in lupus. [J] . Kaveri SV, Mouthon L, Bayry J The New England journal of medicine . 2010,第11期

机译：狼疮中的嗜碱性粒细胞和肾炎。
2. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. [J] . Balabanian K, Couderc J, Bouchet Delbos L, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2003,第6期

机译：趋化因子基质细胞衍生因子1在鼠狼疮自身抗体产生和肾炎中的作用。
3. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. [J] . Balabanian K, Couderc J, Bouchet Delbos L, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2003,第6期

机译：趋化因子基质细胞衍生因子1在鼠狼疮自身抗体产生和肾炎中的作用。
4. Correlation of Eosinofil and Basophil count with intensity of soil transmitted helminth infection among farmers in Bah [C] . P I B Apsari, H Arwati, Y P Dachlan Annual Applied Science and Engineering Conference . 2019

机译：埃斯诺洛尼氏菌和嗜碱性粒细胞计数与土壤强度的相关性传播鲍赫农民的蠕虫感染
5. A mechanism of basophil accumlation in the airways of asthmatics during natural airway narrowing: increased level of basophil chemotactic activity [D] . 丸山修寛 1992

机译：哮喘患者气道在自然气道狭窄期间嗜碱性粒细胞积累的机制：嗜碱性粒细胞趋化活性水平升高
6. Basophils contribute to pristane-induced Lupus-like nephritis model [O] . Barbara Dema, Yasmine Lamri, Christophe Pellefigues, -1

机译：嗜碱性粒细胞促成p烷诱导的狼疮样肾炎模型
7. MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus. [O] . Harald Leiss, Wilhelm Salzberger, Barbara Jacobs, 2017

机译：microRNa 155缺乏导致姥鲛烷诱导的狼疮中自身抗体水平降低和肾炎和肺炎严重程度降低。

Basophils and nephritis in lupus.

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