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首页> 外文期刊>The New Phytologist >Differential selection pressures exerted by host resistance quantitative trait loci on a pathogen population: a case study in an apple x Venturia inaequalis pathosystem
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Differential selection pressures exerted by host resistance quantitative trait loci on a pathogen population: a case study in an apple x Venturia inaequalis pathosystem

机译:宿主抗性定量性状基因座对病原体种群施加的差异选择压力:以苹果x Venturia inaequalis病理系统为例

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Understanding how pathogens evolve according to pressures exerted by their plant hosts is essential for the derivation of strategies aimed at the durable management of resistant culti-vars. The spectrum of action of the resistance factors in the partially resistant cultivars is thought to be an important determinant of resistance durability. However, it has not yet been demonstrated whether the pressures exerted by quantitative resistance are different according to their spectrum of action. To investigate selection pressures exerted by apple genotypes harbouring various resistance quantitative trait loci (QTLs) on a mixed inoculum of the scab disease agent, Venturia inaequalis, we monitored V. inaequalis isolate proportions on diseased apple leavesof an F1 progeny using quantitative pyrosequencing technology and QTL mapping. Broad-spectrum resistances did not exert any differential selection pressures on the mixed inoculum, whereas narrow-spectrum resistances decreased the frequencies of some isolates in the mixture relative to the susceptible host genotypes. Our results suggest that the management of resistant cultivars should be different according to the spectrum of action of their resistance factors. The pyramiding of broad-spectrum factors or the use of a mixture of apple genotypes that carry narrow-spectrum resistance factors are two possible strategies for the minimization of resistance erosion.
机译:了解病原体如何根据其植物宿主施加的压力进行进化,对于制定旨在持久管理抗性品种的策略至关重要。部分抗性品种中抗性因子的作用谱被认为是抗性持久性的重要决定因素。但是,尚未证实定量阻力所施加的压力是否根据作用范围而有所不同。为了研究harbor病病原体Venturia inaequalis的混合接种物中具有各种抗性定量性状位点(QTL)的苹果基因型施加的选择压力,我们使用定量焦磷酸测序技术和QTL监测了F1后代患病苹果叶片上的V. inaequalis分离株比例。映射。广谱抗性没有对混合接种物施加任何差异选择压力,而窄谱抗性相对于易感宿主基因型降低了混合物中某些分离物的频率。我们的结果表明,抗性品种的管理应根据其抗性因子的作用范围而有所不同。广谱因子的金字塔化或携带窄谱抗性因子的苹果基因型混合物的使用是使抗性侵蚀最小化的两种可能策略。

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