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Do centenarians die healthy? An autopsy study.

机译:百岁老人会死得健康吗?尸检研究。

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BACKGROUND: Our goal was to assess the prevalence of common causes of death and the demographic variables in a selected population of centenarians. METHODS: The autopsy reports and medical histories of all individuals > or =100 years, dying unexpectedly out of hospital, were gathered from 42,398 consecutive autopsies, performed over a period of 18 years at the Institute of Forensic Medicine, Vienna. These records were evaluated with regard to age and sex, circumstances of death, season, time and the cause of death, as well as the presence of any other comorbidity. RESULTS: Forty centenarians (11 men, 29 women) were identified with a median age of 102 +/- 2.0 (range: 100-108) years. Sixty percent were described as having been healthy before death. However, an acute organic failure causing death was found in 100%, including cardiovascular diseases in 68%, respiratory illnesses in 25%, gastrointestinal disorders in 5%, and cerebrovascular disease in 2%. Additionally, centenarians suffered from several comorbidities (cardiac antecedents, neurologic disorders, liver diseases, cholecystolithiasis), which were not judged to be the cause of death. CONCLUSIONS: Centenarians, though perceived to have been healthy just prior to death, succumbed to diseases in 100% of the cases examined. They did not die merely "of old age." The 100% post mortem diagnosis of death as a result of acute organic failure justifies autopsy as a legal requirement for this clinically difficult age group.
机译:背景:我们的目标是评估特定百岁老人群体中常见死亡原因的流行程度和人口统计变量。方法:从维也纳法医研究所进行的为期18年的42,398次连续尸检中收集了所有意外死亡或出院的100岁以上的个人的尸检报告和病史。对这些记录进行了评估,包括年龄和性别,死亡情况,季节,时间和死亡原因,以及是否存在其他合并症。结果:确定了40名百岁老人(11名男性,29名女性),中位年龄为102 +/- 2.0(范围:100-108)岁。百分之六十被描述为在死亡之前是健康的。但是,有100%的人发现了导致器质性死亡的急性器质性衰竭,其中心血管疾病占68%,呼吸系统疾病占25%,胃肠道疾病占5%,脑血管疾病占2%。此外,百岁老人患有几种合并症(心脏病前体,神经系统疾病,肝脏疾病,胆囊结石症),但并未被认为是造成死亡的原因。结论:百岁老人虽然在死亡前就被认为是健康的,但在100%的检查病例中死于疾病。他们不仅死于“年老”。死因是急性器质性衰竭的100%验尸后诊断证明,尸体解剖是此临床困难年龄组的法律要求。

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