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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Development and validation of a short portable sarcopenia measure in the African American health project.
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Development and validation of a short portable sarcopenia measure in the African American health project.

机译：在非洲裔美国人健康项目中开发并验证了一种简短的便携式少肌症措施。

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BACKGROUND: Poor muscle size and function (sarcopenia) have an important role in the age-associated disability process. However, no commonly accepted index of sarcopenia exists for use in epidemiological studies. METHODS: A cohort of 998 community-dwelling African Americans 49-65 years' old at baseline was used to construct the short portable sarcopenia measure (SPSM). SPSM was conceptualized as a measure of sarcopenia that combines estimates of muscle quantity and function into a single scale, is based on component items that can be obtained easily in the field, represents muscle status at a single time point that can be used without sex-specific adjustments, and can be used to follow change in muscle status over time with each person as his or her own control. We used exploratory factor analysis (EFA) to identify a unidimensional scale based on timed chair rises, lean mass, and grip strength divided by height. We used these three items and their EFA factor weights to construct SPSM (mean 9.0, median 9, range 0 [worst] to 18 [best] at baseline). Construct validity of the new measure, over a period of 36 months was examined. RESULTS: SPSM required 8.5 pounds of equipment and 12.4 minutes to complete. It showed good score distribution and convergent, discriminant, and predictive validity with measures of muscle function, body composition, physical performance, psychological factors, and functional limitation cross-sectionally and with muscle function and body composition longitudinally. Extensive sensitivity analyses confirmed SPSM's robustness. CONCLUSIONS: SPSM is a brief, portable, and valid measure of sarcopenia for use in epidemiological research. Similar studies in other populations are needed.
机译：背景：不良的肌肉大小和功能（肌肉减少症）在与年龄相关的残疾过程中起重要作用。但是，目前尚无普遍认可的肌肉减少症指数可用于流行病学研究。方法：采用基线时年龄在49-65岁之间的998位居住在社区中的非洲裔美国人队列，构建了简短的便携式少肌症措施（SPSM）。 SPSM被概念化为肌肉减少症的一种测量指标，将肌肉数量和功能的估计值合并为一个尺度，基于可在现场轻松获得的组成项目，代表单个时间点的肌肉状态，无需性别即可使用-特定的调整，并且可以用来跟踪每个人作为自己的控件随时间变化的肌肉状态。我们使用探索性因素分析（EFA）根据定时的椅子上升，瘦体重和抓地力除以身高确定一维尺度。我们使用了这三个项目及其EFA因子权重来构建SPSM（平均9.0，中位数9，范围从0（最差）到18（最佳））。在36个月的时间内检查了新措施的构建有效性。结果：SPSM需要8.5磅的设备和12.4分钟才能完成。它表现出良好的分数分布，并且在横断面测量肌肉功能，身体组成，身体表现，心理因素和功能限制以及纵向在肌肉功能和身体组成方面均具有收敛，判别和预测效度。广泛的敏感性分析证实了SPSM的耐用性。结论：SPSM是一种用于流行病学研究的肌肉减少症的简短，可移植且有效的措施。在其他人群中也需要类似的研究。

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