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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Sleep-disordered breathing and 24-hour blood pressure pattern among older adults.
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Sleep-disordered breathing and 24-hour blood pressure pattern among older adults.

机译：老年人的睡眠呼吸障碍和24小时血压模式。

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BACKGROUND: To examine the association between sleep-disordered breathing (SDB) and 24-hour blood pressure (BP) pattern among community-dwelling older adults. METHODS: A convenience sample of 70 community-dwelling older adults, recruited from senior housing, community centers, and learning centers, were admitted to General Clinical Research Center, Emory University Hospital, Atlanta, Ga. Information regarding demographic and clinical history was obtained using questionnaires. Twenty-four-hour BP monitoring in supine position was performed using Spacelabs model 20207. Breathing during sleep was monitored with the use of a modified sleep recording system (Embletta, PDS), which monitors nasal and oral airflow, chest and abdominal movements, and pulse oximetry. Night time-daytime (night-day) BP ratio (average night-time BP divided by daytime BP) was calculated both for systolic and diastolic BPs. RESULTS: Sixty-nine participants, mean age 74.9 +/- 6.4 years (41 [57%] women), completed the study. The mean apnea-hypopnea index (AHI) was 13 +/- 13 per hour of sleep, and 20 participants (29%) had AHI > or =15 per hour of sleep, indicating moderate to severe SDB. Moderate to severe SDB (AHI > or =15 per hour of sleep) was significantly associated with nocturnal hypertension, whereas there was no statistically significant difference in wake-time BP between those with and without moderate to severe SDB. Stepwise multiple regressions showed that AHI independently predicted increased night-day systolic and night-day diastolic BP ratio, even after controlling for nocturia frequency. CONCLUSIONS: The results indicate increased BP load associated with increased AHI in this group of older adults. This increased BP load may contribute to increased hypertension-related morbidity and disease burden.
机译：摘要背景：研究居住在社区的老年人中睡眠呼吸障碍（SDB）与24小时血压（BP）模式之间的关联。方法：从佐治亚州亚特兰大市埃默里大学医院的一般临床研究中心招募的70名从老年人住房，社区中心和学习中心招募的居住在社区中的老年人作为便利样本。问卷。使用Spacelabs 20207型在仰卧位进行24小时BP监测。使用改进的睡眠记录系统（Embletta，PDS）监测睡眠期间的呼吸，该系统监测鼻腔和口腔的气流，胸部和腹部的运动以及脉搏血氧仪。计算了收缩期和舒张期血压的夜间白天-白天（夜间）BP比率（平均夜间BP除以白天BP）。结果：69名参与者（平均年龄74.9 +/- 6.4岁）（41名[57％]妇女）完成了研究。平均呼吸暂停低通气指数（AHI）为每小时睡眠13 +/- 13，有20名参与者（29％）的AHI>或= 15每小时睡眠，表明中度至重度SDB。中度至重度SDB（每小时AHI>或= 15睡眠）与夜间高血压显着相关，而有中度至重度SDB的患者和没有中度至重度SDB的患者的唤醒时间BP差异均无统计学意义。逐步多元回归分析显示，即使在控制夜尿频度之后，AHI仍独立预测夜间收缩压和夜间舒张压BP比率的增加。结论：结果表明该组老年人的血压负荷增加与AHI增加有关。这种增加的血压负荷可能会导致高血压相关的发病率和疾病负担增加。

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